2. 重组蛋白
  3. Enzymes & Regulators
  4. Matrix Metalloproteinases
  5. MMP-8
  6. MMP-8 蛋白, Cynomolgus (447a.a, HEK293, His)

MMP-8 蛋白, Cynomolgus (447a.a, HEK293, His)

目录号: HY-P700793
产品使用指南

MMP-8，也称为基质金属蛋白酶-8 或胶原酶-2，因其酶促能力而闻名，特别是其分解纤维状 I、II 和 III 型胶原蛋白的能力。这种酶活性表明 MMP-8 在富含胶原蛋白的组织（如结缔组织、软骨和骨）的重塑和周转中发挥着重要作用。MMP-8 蛋白, Cynomolgus (447a.a, HEK293, His) 是重组的 MMP-8 蛋白，由 HEK293 表达，带有 C-His 标签。MMP-8 蛋白, Cynomolgus (447a.a, HEK293, His) 全长 447 个氨基酸，分子量为 60-70 kDa。

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100 μg   询价  

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描述

MMP-8, also known as matrix metalloproteinase-8 or collagenase-2, is recognized for its enzymatic abilities, particularly its ability to break down fibrillar types I, II, and III collagen. This enzymatic activity suggests that MMP-8 plays an important role in the remodeling and turnover of collagen-rich tissues such as connective tissue, cartilage, and bone. MMP-8 Protein, Cynomolgus (447a.a, HEK293, His) is the recombinant cynomolgus-derived MMP-8 protein, expressed by HEK293 , with C-His labeled tag. The total length of MMP-8 Protein, Cynomolgus (447a.a, HEK293, His) is 447 a.a., with molecular weight of 60-70 kDa.
研究背景

MMP-8，也称为基质金属蛋白酶-8 或胶原酶-2，因其酶促能力，特别是其分解纤维状 I、II 和 III 型胶原蛋白的能力而受到认可。这种酶活性表明 MMP-8 在富含胶原蛋白的组织（如结缔组织、软骨和骨）的重塑和周转中发挥着重要作用。通过降解这些纤维状胶原蛋白，MMP-8 可以促进组织重塑、伤口愈合和炎症消退等过程。了解 MMP-8 的精确功能和调节可以为其参与胶原蛋白代谢和组织重塑提供有价值的见解，从而可能为以异常胶原蛋白降解或积累为特征的疾病提供治疗机会。
种属

Cynomolgus
表达系统

HEK293
标签

C-His
蛋白编号

XP_005579523.2 (F21-S467)
基因 ID
蛋白结构
N-term
MMP-8 (F21-S467)
Accession # XP_005579523.2
His
C-term
同用名
PMNL-CL; CLG1; MMP8; Collagenase 2; PMNL-CL; HNC
分子量

60-70 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

MMP-8 Protein, Cynomolgus (447a.a, HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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