NXPH1 蛋白, Rat (HEK293, His)

The NXPH1 protein is similar to a neuropeptide and acts as a signaling molecule by binding to alpha-neurotoxins. Its ligand action is suggested to mediate cell signaling through interactions with neuronal cell adhesion proteins. NXPH1 Protein, Rat (HEK293, His) is the recombinant rat-derived NXPH1 protein, expressed by HEK293 , with C-His labeled tag. The total length of NXPH1 Protein, Rat (HEK293, His) is 250 a.a., with molecular weight of 43-55 kDa.

NXPH1 蛋白似乎起到信号分子的作用，其特征让人想起神经肽。它被鉴定为 α-neurexins 的配体，表明通过与这些神经元细胞粘附蛋白的相互作用介导细胞信号传导。NXPH1 作为信号传导实体的潜在意义强调了它在神经通讯中的重要性，并暗示它通过与 α-neurexins 相互作用参与调节细胞过程。进一步探索 NXPH1 与 α-neurexins 相互作用的具体机制和下游效应，可以为了解其在更广泛的神经生物学背景中的作用提供有价值的见解。

Measured in a competitive binding assay. When Neurexin-1 alpha is immobilized at 1 µg/mL (100 µL/well), Neurexophilin-1 inhibits binding of biotinylated Neurexophilin-1 (1 µg/mL). The IC₅₀ for this effect is 0.1095 μg/mL.

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  Measured in a competitive binding assay. When Neurexin-1 alpha is immobilized at 1 µg/mL (100 µL/well), Neurexophilin-1 inhibits binding of biotinylated Neurexophilin-1 (1 µg/mL) .The IC₅₀ for this effect is 0.1095 μg/mL.

Rat

HEK293

C-6*His

Q63366 (A22-G271)

25501  [NCBI]

ANLTNGGKSELLKSGNSKSTLKHIWTESSKDLSISRLLSQTFRGKENGTDLDLRYDTPEPYSEQDLWDWLRNSTDLQEPRPRAKRRPIVKTGKFKKMFGWGDFHSNIKTVKLNLLITGKIVDHGNGTFSVYFRHNSTGQGNVSVSLVPPTKIVEFDLAQQTVIDAKDSKSFNCRIEYEKVDKATKNTLCNYDPSKTCYQEQTQSHVSWLCSKPFKVICIYISFYSTDYKLVQKVCPDYNYHSDTPYFPSG

Approximately 43-55 kDa due to the glycosylation

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  Greater than 90% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.