1. 重组蛋白
  2. Fluorescent-labeled Recombinant Proteins Others
  3. PE-Labeled HLA-A*1101 KRAS Complex 蛋白, Human (VVGADGVGK, HEK293)

PE-Labeled HLA-A*1101 KRAS Complex 蛋白, Human (VVGADGVGK, HEK293)

目录号: HY-P701300
产品使用指南

HLA-A*1101是MHC I类家族的重要成员,在抗原呈递和免疫监视中发挥重要作用。该复合物与 HLA-A*1101 等位基因相连,并主动向细胞毒性 T 淋巴细胞呈递抗原肽,显着促进免疫反应。PE-Labeled HLA-A*1101 KRAS Complex 蛋白, Human (VVGADGVGK, HEK293) 是重组的蛋白二聚体复合物,包含 HLA-A*1101 和 B2M/Beta-2-microglobulin Protein,由 HEK293 表达,带有 标签。 和 VVGADGVGK Y:Y。PE-Labeled HLA-A*1101 KRAS Complex 蛋白, Human (VVGADGVGK, HEK293) ,分子量为 55-60 kDa。

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描述

HLA-A*1101 is an important member of the MHC class I family and plays an important role in antigen presentation and immune surveillance. This complex is linked to the HLA-A*1101 allele and actively presents antigenic peptides to cytotoxic T lymphocytes, significantly promoting immune responses. PE-Labeled HLA-A*1101 KRAS Complex Protein, Human (VVGADGVGK, HEK293) is a recombinant protein dimer complex containing HLA-A*1101 and B2M/Beta-2-microglobulin Protein, expressed by HEK293 , with labeled tag and VVGADGVGK peptide. PE-Labeled HLA-A*1101 KRAS Complex Protein, Human (VVGADGVGK, HEK293), has molecular weight of 55-60 kDa.

研究背景

HLA-A*1101 是 MHC I 类家族的重要成员,在抗原呈递和免疫监视中发挥着关键作用。这种复合蛋白的特点是与 HLA-A*1101 等位基因相关,它积极参与向细胞毒性 T 淋巴细胞呈递抗原肽,对免疫反应的协调做出了重大贡献。PE 标记增加了其抗原结合能力的特异性,可能影响表达 KRAS 抗原的癌症中的免疫反应。作为 MHC I 类家族的一部分,HLA-A*1101 强调了其在增进我们对免疫过程的理解方面的重要性,并有望在 KRAS 相关恶性肿瘤背景下的抗原呈递和免疫系统动力学研究中得到应用。

种属

Human

表达系统

HEK293

蛋白编号

Q5S3G3 (G25-T305)&P61769 (I21-M119)&VVGADGVGK

基因 ID

3105&567

同用名
HLA-A*1101; B2M; KRAS; VVGADGVGK
分子量

55-60 kDa

纯度

/

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

PE-Labeled HLA-A*1101 KRAS Complex Protein, Human (VVGADGVGK, HEK293) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
PE-Labeled HLA-A*1101 KRAS Complex Protein, Human (VVGADGVGK, HEK293)
目录号:
HY-P701300
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