1. 重组蛋白
  2. Enzymes & Regulators
  3. Phosphatase
  4. PPP1R14A 蛋白, Human (His)

PPP1R14A 蛋白, Human (His)

目录号: HY-P71229
产品使用指南

PPP1R14A 蛋白是一种关键的细胞调节因子,可有效抑制 PPP1CA,并在磷酸化后表现出显着的活性放大。这种磷酸化诱导的转化将 PPP1R14A 转变为善于调节 PPP1CA 底物磷酸化的动态分子开关。PPP1R14A 蛋白, Human (His) 是重组的 PPP1R14A 蛋白,由 E. coli 表达,带有 C-6*His 标签。PPP1R14A 蛋白, Human (His) 全长 147 个氨基酸,分子量为 23-26 kDa。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

The PPP1R14A protein is a key cellular regulator that effectively inhibits PPP1CA and exhibits significant activity amplification upon phosphorylation. This phosphorylation-induced transformation turns PPP1R14A into a dynamic molecular switch adept at regulating PPP1CA substrate phosphorylation. PPP1R14A Protein, Human (His) is the recombinant human-derived PPP1R14A protein, expressed by E. coli , with C-6*His labeled tag. The total length of PPP1R14A Protein, Human (His) is 147 a.a., with molecular weight of 23-26 kDa.

研究背景

PPP1R14A 是细胞调节的关键参与者,是 PPP1CA 的有效抑制剂。其抑制能力占据中心地位,磷酸化后活性增加了千倍以上。这种磷酸化诱导的增强将 PPP1R14A 转化为分子开关,这是一种善于调节 PPP1CA 底物磷酸化状态的动态调节器。在错综复杂的细胞信号传导中,PPP1R14A 成为关键的协调者,在平滑肌收缩领域尤其具有影响力。这种多方面的作用使 PPP1R14A 成为控制细胞过程的复杂机制中的关键元素,并为细胞信号传导的动态景观添加了一层细致入微的控制。

种属

Human

表达系统

E. coli

标签

C-6*His

蛋白编号

Q96A00 (M1-P147)

基因 ID
蛋白结构
N-term
PPP1R14A (M1-P147)
Accession # Q96A00
6*His
C-term
同用名
Protein Phosphatase 1 Regulatory Subunit 14A; 17 kDa PKC-Potentiated Inhibitory Protein of PP1; Protein Kinase C-Potentiated Inhibitor Protein of 17 kDa; CPI-17; PPP1R14A; CPI17; PPP1INL
氨基酸序列

MAAQRLGKRVLSKLQSPSRARGPGGSPGGLQKRHARVTVKYDRRELQRRLDVEKWIDGRLEELYRGMEADMPDEINIDELLELESEEERSRKIQGLLKSCGKPVEDFIQELLAKLQGLHRQPGLRQPSPSHDGSLSPLQDRARTAHP

分子量

23-26 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

PPP1R14A Protein, Human (His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
PPP1R14A Protein, Human (His)
目录号:
HY-P71229
需求量: