1. 重组蛋白
  2. CD Antigens
  3. Stem Cell CD Proteins Epithelial cell CD Proteins
  4. PSBG1 Protein/CD66f
  5. PSG1 蛋白, Human (HEK 293, hFc)

PSG1 蛋白, Human (HEK 293, hFc)

目录号: HY-P72486A
COA 产品使用指南

妊娠特异性 β-1-糖蛋白 1 (PSG1) 源自合体滋养层,足月孕妇血清中的浓度达到 100 至 290 mg/l。作为人类胎盘的重要组成部分,PSG1 在免疫球蛋白 (Ig) 超家族中的分子特征有助于其在支持妊娠方面发挥重要作用。PSG1 的限制性表达主要位于胎盘 (RPKM 224.3),强调了其作为妊娠期间胎儿生存和发育所必需的激素环境的主要贡献者的重要性。PSG1 蛋白, Human (HEK 293, hFc) 是重组的 PSG1 蛋白,由 HEK293 表达,带有 C-hFc 标签。PSG1 蛋白, Human (HEK 293, hFc) 全长 385 个氨基酸,分子量约为 ~95 KDa。

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  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

Pregnancy-specific beta-1-glycoprotein 1 (PSG1), originating from the syncytiotrophoblast, attains concentrations of 100 to 290 mg/l in the serum of pregnant women at term. As a vital component of the human placenta, PSG1's molecular characteristics, within the immunoglobulin (Ig) superfamily, contribute to its essential role in supporting pregnancy. With a restricted expression primarily localized to the placenta (RPKM 224.3), PSG1 underscores its significance as a major contributor to the hormonal milieu essential for fetal survival and development during pregnancy. PSG1 Protein, Human (HEK 293, hFc) is the recombinant human-derived PSG1 protein, expressed by HEK293, with C-hFc labeled tag. The total length of PSG1 Protein, Human (HEK 293, hFc) is 385 a.a., with molecular weight of ~95 KDa.

研究背景

妊娠特异性 β-1-糖蛋白 1 (PSG1) 是人类胎盘的主要成分,胎盘是维持胎儿健康的重要内分泌器官。PSG1 源自合体滋养层,在足月孕妇的血清中浓度达到 100 至 290 mg/l。PSG1 属于免疫球蛋白 (Ig) 超家族,其分子特征有助于其在支持妊娠方面发挥重要作用。PSG1 的限制性表达主要位于胎盘 (RPKM 224.3),强调了其作为妊娠期间胎儿生存和发育所必需的激素环境的主要贡献者的重要性。

生物活性

Data is not available.

种属

Human

表达系统

HEK293

标签

C-hFc

蛋白编号

NP_001171754.1 (Q35-P419)

基因 ID

5669

蛋白结构
N-term
PSG1 (Q35-P419)
Accession # NP_001171754.1
hFc
C-term
同用名
PSG1; Pregnancy-specific beta-1-glycoprotein 1
分子量

Approximately 95 kDa.

纯度
  • Greater than 90% as determined by reducing SDS-PAGE.
性状

无菌粉末

组分

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
PSG1 Protein, Human (HEK 293, hFc)
目录号:
HY-P72486A
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