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  4. PTX3 蛋白, Mouse (HEK293, His)

PTX3 蛋白, Mouse (HEK293, His)

目录号: HY-P71246
COA 产品使用指南

PTX3 蛋白在先天病原体抵抗和炎症调节中至关重要，可能有助于自身成分清除和女性生育能力。作为具有二硫键连接结构的同八聚体，PTX3 的多面性可维持免疫稳态。与 C1q 的相互作用强调了其在先天免疫反应中的重要性，将 PTX3 定位为病原体防御和炎症调节的关键参与者。PTX3 蛋白, Mouse (HEK293, His) 是重组的 PTX3 蛋白，由 HEK293 表达，带有 N-6*His 标签。PTX3 蛋白, Mouse (HEK293, His) 全长 364 个氨基酸，分子量约为 ~54.0 kDa。

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规格 价格 是否有货 数量
10 μg ￥1700 In-stock
50 μg ￥5100 询价
100 μg   询价  

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描述

PTX3 Protein, pivotal in innate pathogen resistance and inflammation regulation, may contribute to self-component clearance and female fertility. As a homooctamer with disulfide-linked structures, PTX3's multifaceted nature maintains immune homeostasis. Interaction with C1q underscores its significance in innate immune responses, positioning PTX3 as a key player in pathogen defense and inflammatory modulation. PTX3 Protein, Mouse (HEK293, His) is the recombinant mouse-derived PTX3 protein, expressed by HEK293 , with N-6*His labeled tag. The total length of PTX3 Protein, Mouse (HEK293, His) is 364 a.a., with molecular weight of ~54.0 kDa.
研究背景

PTX3 蛋白在协调对病原体的先天抵抗力、调节炎症反应、可能有助于清除自身成分以及参与女性生育能力方面发挥着关键作用。PTX3 作为具有二硫键连接结构的同八聚体存在，表现出维持免疫稳态所必需的多方面性质。值得注意的是，它与 C1q 的相互作用强调了它在复杂的先天免疫反应网络中的重要性，强调 PTX3 在防御病原体和调节炎症过程中发挥着关键作用。
种属

Mouse
表达系统

HEK293
标签

N-6*His
蛋白编号

P48759 (E18-S381)
基因 ID

19288  [NCBI]
蛋白结构
N-term
6*His
PTX3 (E18-S381)
Accession # P48759
C-term
同用名
alpha-induced protein 5; pentaxin-related gene, rapidly induced by IL-1 beta, tumor necrosis factor; Pentaxin-related protein PTX3; Pentraxin 3; pentraxin 3, long; pentraxin-3; pentraxin-related gene, rapidly induced by IL-1 beta; pentraxin-related protein PTX3;
氨基酸序列

ETSDDYELMYVNLDNEIDNGLHPTEDPTPCDCRQEHSEWDKLFIMLENSQMREGMLLQATDDVLRGELQRLRAELGRLAGGMARPCAAGGPADARLVRALEPLLQESRDASLRLARLEDAEARRPEATVPGLGAVLEELRRTRADLSAVQSWVARHWLPAGCETAIFFPMRSKKIFGSVHPVRPMKLESFSTCIWVKATDVLNKTILFSYGTKWNPYEIQLYLSSQSLVLVVGGKENKLAADTVVSLGRWSHLCGTWSSEQGSMSLWANGELVATTVEMAKSHSVPEGGLLQIGQEKNGCCVGGGFDESLAFSGRITGFNIWDRVLSEEEIRASGGVESCHIRGNVVGWGVTEIQAHGGAQYVS

分子量

Approximately 54.0 kDa
纯度

Greater than 90% as determined by reducing SDS-PAGE.
性状

溶液.
组分

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.
内毒素含量

<1 EU/μg, determined by LAL method.
保存条件 & 期限

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.
运输条件

Shipping with dry ice.
文件资料

COA (209 KB)

产品使用指南 (1213 KB)

PTX3 Protein, Mouse (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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