2. 重组蛋白
  3. Enzymes & Regulators
  4. PXK 蛋白, Human (Sf9, His, GST)

PXK 蛋白, Human (Sf9, His, GST)

目录号: HY-P701763
产品使用指南

PXK 蛋白结合并调节大脑 Na,K-ATP 酶亚基 ATP1B1 和 ATP1B3，表明其在调节神经电兴奋性和突触传递中具有潜在作用。尽管缺乏激酶活性，PXK 与这些亚基的相互作用表明其在神经过程中具有调节功能，强调其对控制大脑神经元功能和通讯的复杂机制的潜在贡献。PXK 蛋白, Human (Sf9, His, GST) 是重组的 PXK 蛋白，由 Sf9 insect cells 表达，带有 N-8*His, N-GST 标签。PXK 蛋白, Human (Sf9, His, GST) 全长 577 个氨基酸。

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规格 是否有货
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100 μg   询价  

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描述

PXK protein binds to and modulates brain Na,K-ATPase subunits ATP1B1 and ATP1B3, indicating a potential role in regulating neural electrical excitability and synaptic transmission. Despite lacking kinase activity, PXK's interaction with these subunits suggests a regulatory function in neural processes, emphasizing its potential contribution to the complex mechanisms governing brain neuronal function and communication. PXK Protein, Human (Sf9, His, GST) is the recombinant human-derived PXK protein, expressed by Sf9 insect cells , with N-8*His, N-GST labeled tag. The total length of PXK Protein, Human (Sf9, His, GST) is 577 a.a., .
研究背景

PXK 蛋白表现出对脑 Na,K-ATP 酶亚基 ATP1B1 和 ATP1B3 的结合亲和力和调节作用，可能在脑内电兴奋性和突触传递的调节中发挥关键作用。虽然其精确的分子功能可能不涉及激酶活性，但它与这些 Na,K-ATP 酶亚基的相互作用表明其在神经过程中具有调节作用，强调 PXK 作为控制大脑神经元功能和通讯的复杂机制的潜在贡献者。
种属

Human
表达系统

Sf9 insect cells
标签

N-8*His;N-GST
蛋白编号

Q7Z7A4 (A2-G578)
基因 ID

54899
蛋白结构
N-term
8*His-GST
PXK (A2-G578)
Accession # Q7Z7A4
C-term
同用名
PXK; PX domain-containing protein kinase-like protein; Modulator of Na; K-ATPase; MONaKA
纯度

Greater than 90% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

PXK Protein, Human (Sf9, His, GST) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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