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  3. RBP4 蛋白, Mouse (HEK293, hFc)

RBP4 蛋白, Mouse (HEK293, hFc)

目录号: HY-P700437
产品使用指南

RBP4 蛋白转运血浆中的视黄醇,将其从肝脏储存输送到周围组织。它与全反式视黄醇结合,将其转移至 STRA6 以实现有效的细胞膜运输。RBP4 与 TTR 相互作用,防止肾脏过滤,并进一步支持 STRA6 的视黄醇转运。RBP4 蛋白, Mouse (HEK293, hFc) 是重组的 RBP4 蛋白,由 HEK293 表达,带有 C-hFc 标签。RBP4 蛋白, Mouse (HEK293, hFc) 全长 183 个氨基酸,分子量为 50.3 kDa。

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描述

RBP4 Protein transports retinol in blood plasma, delivering it from liver stores to peripheral tissues. Binding to all-trans retinol, it transfers it to STRA6 for efficient cell membrane transport. RBP4 interacts with TTR, preventing kidney filtration, and further supports STRA6 in retinol transport. RBP4 Protein, Mouse (HEK293, hFc) is the recombinant mouse-derived RBP4 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of RBP4 Protein, Mouse (HEK293, hFc) is 183 a.a., with molecular weight of 50.3 kDa.

研究背景

RBP4 蛋白是一种重要的视黄醇结合蛋白,负责在血浆中运输视黄醇。它在将视黄醇从肝脏储存输送到周围组织方面发挥着至关重要的作用。RBP4 与全反式视黄醇结合并将其转移至 STRA6,从而促进视黄醇跨细胞膜的有效运输。此外,RBP4 与 TTR 相互作用,防止其通过肾小球过滤而损失。此外,RBP4 还与 STRA6 相互作用,进一步促进其在视黄醇转运中的作用。

种属

Mouse

表达系统

HEK293

标签

C-hFc

蛋白编号

Q00724 (E19-L201)

基因 ID

19662  [NCBI]

蛋白结构
N-term
RBP4 (E19-L201)
Accession # Q00724
hFc
C-term
同用名
retinol-binding protein 4
氨基酸序列

ERDCRVSSFRVKENFDKARFSGLWYAIAKKDPEGLFLQDNIIAEFSVDEKGHMSATAKGRVRLLSNWEVCADMVGTFTDTEDPAKFKMKYWGVASFLQRGNDDHWIIDTDYDTFALQYSCRLQNLDGTCADSYSFVFSRDPNGLSPETRRLVRQRQEELCLERQYRWIEHNGYCQSRPSRNSL

分子量

50.3 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

RBP4 Protein, Mouse (HEK293, hFc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
RBP4 Protein, Mouse (HEK293, hFc)
目录号:
HY-P700437
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