Resistin 蛋白, Human (His)

Resistin, a hormone linking obesity to diabetes, may hinder insulin's glucose uptake stimulation in adipose cells, contributing to metabolic dysregulation. Additionally, it promotes myeloid cell chemotaxis and forms homodimers through disulfide linkages, interacting with DEFA1. Resistin's involvement in diverse cellular processes suggests its pivotal role in the complex interplay of metabolism, inflammation, and insulin responsiveness. Resistin Protein, Human (His) is the recombinant human-derived Resistin protein, expressed by E. coli , with C-6*His labeled tag. The total length of Resistin Protein, Human (His) is 90 a.a., with molecular weight of 10-14 kDa.

抵抗素是一种与肥胖和糖尿病有关的激素，它通过潜在地抑制胰岛素刺激脂肪细胞摄取葡萄糖的能力来发挥作用。它不仅在代谢调节中发挥作用，而且还促进骨髓细胞的趋化性。在结构上，Resistin 通过二硫键形成同二聚体并与 DEFA1 相互作用，表明它参与多种细胞过程。这种多方面的激素在新陈代谢、炎症和胰岛素反应性之间复杂的相互作用中发挥着潜在的关键作用。

Human

E. coli

C-6*His

Q9HD89 (K19-P108)

56729  [NCBI]

KTLCSMEEAINERIQEVAGSLIFRAISSIGLECQSVTSRGDLATCPRGFAVTGCTCGSACGSWDVRAETTCHCQCAGMDWTGARCCRVQP

10-14 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of 20 mM Acetic acid, pH 3.0.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US;may vary elsewhere.