SPINK4 蛋白, Mouse (HEK293, His)

The SPINK4 protein acts as a serine-type endopeptidase inhibitor, regulating peptidase activity. It is located in the extracellular region, suggesting that it has inhibitory functions outside the cell. SPINK4 Protein, Mouse (HEK293, His) is the recombinant mouse-derived SPINK4 protein, expressed by HEK293 , with C-His, C-6*His labeled tag. The total length of SPINK4 Protein, Mouse (HEK293, His) is 60 a.a., with molecular weight of ~8-11 kDa.

SPINK4 蛋白预计将作为丝氨酸型内肽酶抑制剂发挥至关重要的作用，表明其参与肽酶活性的复杂调节。通过预测在细胞外区域的位置，该蛋白质可以在细胞外环境中发挥其抑制功能。它在不同组织中的表达，包括脑室层、神经节、肝叶和嗅觉上皮，强调了它在各种生理过程中的潜在参与。大肠和结肠成体组织中的偏向表达强调了其在消化系统内局部调节机制中的潜在作用。与人类 SPINK4 的直系同源关系被鉴定为 Kazal 4 型丝氨酸肽酶抑制剂，进一步支持其跨物种功能意义的进化保守性。

Mouse

HEK293

C-His;C-6*His

NP_035593.2 (G27-C86)

20731  [NCBI]

GSLVFPRMPFCEHMAELPNCPQTPNLICGTDGLTYENECHLCLTRMKTMKDIQIMKDGQC

Approximately 8-11 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.