STEAP2 蛋白, Human (Cell-Free, His, SUMO)

The integral membrane protein, STEAP2, acts as an NADPH-dependent ferric-chelate reductase, facilitating transmembrane electron transfer. It employs NADPH to reduce Fe(3+) chelate, involving sequential electron transfer from NADPH to FAD and then to heme. STEAP2 also demonstrates the ability to reduce Cu(2+) to Cu(1+), showcasing its versatility in transmembrane electron transfer processes. STEAP2 Protein, Human (Cell-Free, His, SUMO) is the recombinant human-derived STEAP2 protein, expressed by E. coli Cell-free , with N-10*His, N-SUMO labeled tag. The total length of STEAP2 Protein, Human (Cell-Free, His, SUMO) is 490 a.a., with molecular weight of 74.6 kDa.

STEAP2 蛋白是一种完整的膜蛋白，充当 NADPH 依赖性铁螯合物还原酶，利用膜一侧的 NADPH 还原结合在另一侧的 Fe(3+) 螯合物。通过顺序跨膜电子转移，STEAP2 促进电子从 NADPH 转移到 FAD，然后转移到血红素上，最终还原 Fe(3+) 螯合物。此外，STEAP2 还具有将 Cu(2+) 还原为 Cu(1+) 的能力，增强了其作为跨膜电子转移过程中介者的多功能性。

Human

E. coli Cell-free

N-10*His;N-SUMO

Q8NFT2 (M1-M490)

261729

MESISMMGSPKSLSETFLPNGINGIKDARKVTVGVIGSGDFAKSLTIRLIRCGYHVVIGSRNPKFASEFFPHVVDVTHHEDALTKTNIIFVAIHREHYTSLWDLRHLLVGKILIDVSNNMRINQYPESNAEYLASLFPDSLIVKGFNVVSAWALQLGPKDASRQVYICSNNIQARQQVIELARQLNFIPIDLGSLSSAREIENLPLRLFTLWRGPVVVAISLATFFFLYSFVRDVIHPYARNQQSDFYKIPIEIVNKTLPIVAITLLSLVYLAGLLAAAYQLYYGTKYRRFPPWLETWLQCRKQLGLLSFFFAMVHVAYSLCLPMRRSERYLFLNMAYQQVHANIENSWNEEEVWRIEMYISFGIMSLGLLSLLAVTSIPSVSNALNWREFSFIQSTLGYVALLISTFHVLIYGWKRAFEEEYYRFYTPPNFVLALVLPSIVILGKIILFLPCISRKLKRIKKGWEKSQFLEEGMGGTIPHVSPERVTVM

74.6 kDa

Greater than 90% as determined by reducing SDS-PAGE.

<1 EU/μg, determined by LAL method.