1. 重组蛋白
  2. Cytokines and Growth Factors Receptor Proteins Enzymes & Regulators
  3. TGF-beta Superfamily Receptor Serine/Threonine Kinases Serine/Threonine Kinase Proteins
  4. TGF-beta Receptor Type III TGF-β Receptor
  5. TGFBR3/TGF-beta RIII 蛋白, Human (sf9, His)

TGFBR3/TGF-beta RIII 蛋白, Human (sf9, His)

目录号: HY-P74521
产品使用指南

TGFBR3/TGF-β RIII 蛋白至关重要,可与 TGF-β 结合,表明在捕获 TGF-β 并将其呈递给信号受体方面具有潜在作用。在促性腺细胞中,它充当抑制素 A 辅助受体,调节 FSH 水平并影响女性生育能力。它与 DYNLT4 的相互作用强调了细胞过程中的多种功能关联,表明 TGFBR3 在细胞调节和生育控制中发挥多方面的作用。TGFBR3/TGF-beta RIII 蛋白, Human (sf9, His) 是重组的 TGFBR3/TGF-β RIII 蛋白,由 Sf9 昆虫细胞表达,带有 C-His 标签。TGFBR3/TGF-beta RIII 蛋白, Human (sf9, His) 全长 761 个氨基酸,分子量约为 ~88 kDa。

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描述

TGFBR3/TGF-beta RIII Protein is pivotal, binding to TGF-beta, indicating a potential role in capturing and presenting TGF-beta to signaling receptors. In gonadotrope cells, it acts as an inhibin A coreceptor, regulating FSH levels and impacting female fertility. Its interaction with DYNLT4 emphasizes diverse functional associations in cellular processes, suggesting a multifaceted role for TGFBR3 in cellular regulation and fertility control. TGFBR3/TGF-beta RIII Protein, Human (sf9, His) is the recombinant human-derived TGFBR3/TGF-beta RIII protein, expressed by Sf9 insect cells, with C-His labeled tag. The total length of TGFBR3/TGF-beta RIII Protein, Human (sf9, His) is 761 a.a., with molecular weight of ~88 kDa.

研究背景

TGFBR3/TGF-β RIII 蛋白在与 TGF-β 结合时发挥着关键作用,这表明它可能参与捕获和保留 TGF-β 以呈递给信号传导受体,正如与相关蛋白的相似性所推断的那样。特别是在促性腺细胞中,TGFBR3 充当抑制素 A 辅助受体,对卵泡刺激素 (FSH) 水平进行调节控制并影响女性生育力,相关研究表明。此外,TGFBR3 与 DYNLT4 相互作用,强调了其在细胞过程中的多种功能关联。

种属

Human

表达系统

Sf9 insect cells

标签

C-His

蛋白编号

Q03167 (G21-G781)

基因 ID
蛋白结构
N-term
TGFBR3 (G21-G781)
Accession # Q03167
His
C-term
同用名
TGFBR3; TGF-bRIII; TGFR-3; Transforming growth factor beta receptor III; Betaglycan
分子量

Approximately 88 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
TGFBR3/TGF-beta RIII Protein, Human (sf9, His)
目录号:
HY-P74521
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