2. 重组蛋白
  3. CD Antigens Receptor Proteins
  4. T Cell CD Proteins Monocyte CD Proteins Epithelial cell CD Proteins Pattern Recognition Receptors
  5. CD282/TLR2 Toll-like Receptor
  6. Toll Like Receptor 2
  7. TLR2 蛋白, Rat (sf9, His)

TLR2 蛋白, Rat (sf9, His)

目录号: HY-P73589
产品使用指南

TLR2 蛋白与 LY96 配合，启动针对细菌脂蛋白和微生物细胞壁成分的先天免疫反应。它还与TLR1或TLR6配合对细菌脂蛋白或脂肽产生免疫反应。这涉及 NF-kappa-B 激活、细胞因子分泌以及通过 MYD88 和 TRAF6 信号通路诱导炎症反应。TLR2 蛋白, Rat (sf9, His) 是重组的 TLR2 蛋白，由 Sf9 insect cells 表达，带有 C-His 标签。TLR2 蛋白, Rat (sf9, His) 全长 587 个氨基酸，分子量约为 ~60 kDa。

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重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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100 μg   询价  

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描述

TLR2 Protein cooperates with LY96 to initiate innate immune response against bacterial lipoproteins and microbial cell wall components. It also cooperates with TLR1 or TLR6 for the immune response to bacterial lipoproteins or lipopeptides. This involves NF-kappa-B activation, cytokine secretion, and induction of inflammatory response via MYD88 and TRAF6 signaling pathways. TLR2 Protein, Rat (sf9, His) is the recombinant rat-derived TLR2 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of TLR2 Protein, Rat (sf9, His) is 587 a.a., with molecular weight of ~60 kDa.
研究背景

TLR2 蛋白与 LY96 协同作用，启动针对细菌脂蛋白和其他微生物细胞壁成分的先天免疫反应。它还与 TLR1 或 TLR6 配合，对细菌脂蛋白或脂肽产生先天免疫反应。该过程涉及 NF-kappa-B 的激活、细胞因子的分泌以及通过涉及 MYD88 和 TRAF6 的信号通路诱导炎症反应。
种属

Rat
表达系统

Sf9 insect cells
标签

C-His
蛋白编号

Q6YGU2 (M1-Q587)
基因 ID
蛋白结构
N-term
TLR2 (M1-Q587)
Accession # Q6YGU2
His
C-term
同用名
CD282; TIL4; TLR2; Toll-like receptor 2
分子量

Approximately 60 kDa
纯度

Greater than 90% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

TLR2 Protein, Rat (sf9, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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