2. 重组蛋白
  3. Receptor Proteins Enzymes & Regulators
  4. Receptor Tyrosine Kinases Protein Tyrosine Kinases
  5. Trk Receptors TrkB
  6. TrkB 蛋白, Mouse (429a.a, HEK293, His)

TrkB 蛋白, Mouse (429a.a, HEK293, His)

目录号: HY-P73463
产品使用指南

TrkB 蛋白，也称为原肌球蛋白受体激酶 B，由非催化亚型组成。与其催化亚型不同，TrkB 的非催化亚型缺乏内在的激酶活性。TrkB 蛋白, Mouse (429a.a, HEK293, His) 是重组的 TrkB 蛋白，由 HEK293 表达，带有 C-His 标签。TrkB 蛋白, Mouse (429a.a, HEK293, His) 全长 429 个氨基酸，分子量为 75-85 kDa。

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     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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该产品已“停产”。 等效替代： HY-P72436

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描述

TrkB protein, also known as tropomyosin receptor kinase B, consists of a non-catalytic isoform. Unlike its catalytic isoform, the noncatalytic isoform of TrkB lacks intrinsic kinase activity. TrkB Protein, Mouse (429a.a, HEK293, His) is the recombinant mouse-derived TrkB protein, expressed by HEK293 , with C-His labeled tag. The total length of TrkB Protein, Mouse (429a.a, HEK293, His) is 429 a.a., with molecular weight of 75-85 kDa.
研究背景

TrkB 蛋白，也称为原肌球蛋白受体激酶 B，由非催化亚型组成。与其催化亚型不同，TrkB 的非催化亚型缺乏内在激酶活性。TrkB 的催化亚型负责在其配体（例如脑源性神经营养因子 (BDNF)）激活后启动信号级联反应。然而，TrkB 的非催化异构体被认为可以调节催化异构体的活性并调节其信号通路。虽然 TrkB 非催化亚型的确切作用仍在研究中，但人们认为它在各种细胞过程中发挥调节作用，特别是在神经元发育和突触可塑性中。需要进一步的研究来充分阐明 TrkB 非催化亚型的功能意义及其对神经元功能的贡献。
种属

Mouse
表达系统

HEK293
标签

C-His
蛋白编号

P15209-2 (M1-H429)
基因 ID
蛋白结构
N-term
TrkB (M1-H429)
Accession # P15209-2
His
C-term
同用名
BDNF/NT-3 Growth Factors Receptor; Trk-B; NTRK2; TRKB
分子量

75-85 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

TrkB Protein, Mouse (429a.a, HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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