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  3. TXNDC12 蛋白, Human (HEK293, His)

TXNDC12 蛋白, Human (HEK293, His)

目录号: HY-P71046
产品使用指南

TXNDC12蛋白是一种重要的内质网定位蛋白二硫键还原酶,在促进客户蛋白二硫键形成中发挥关键作用。作为细胞机器的重要组成部分,TXNDC12 有助于复杂的蛋白质折叠过程,突出了其在维持正确的蛋白质结构和功能方面的重要性。TXNDC12 蛋白, Human (HEK293, His) 是重组的 TXNDC12 蛋白,由 HEK293 表达,带有 C-6*His 标签。TXNDC12 蛋白, Human (HEK293, His) 全长 142 个氨基酸,分子量约为 ~18.0 kDa。

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描述

The TXNDC12 protein is an important endoplasmic reticulum-localized protein disulfide bond reductase that plays a key role in promoting disulfide bond formation in client proteins. As an essential component of cellular machinery, TXNDC12 contributes to complex protein folding processes, highlighting its importance in maintaining correct protein structure and function. TXNDC12 Protein, Human (HEK293, His) is the recombinant human-derived TXNDC12 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of TXNDC12 Protein, Human (HEK293, His) is 142 a.a., with molecular weight of ~18.0 kDa.

研究背景

TXNDC12蛋白是一种位于内质网的重要蛋白二硫键还原酶,凭借其硫醇二硫键氧化酶活性,在促进客户蛋白中二硫键的形成中发挥着关键作用。作为细胞机器的重要组成部分,TXNDC12 参与内质网内蛋白质折叠和成熟的复杂过程。其促进二硫键形成的催化功能强调了其在维持适当的蛋白质结构和功能方面的重要性,反映了其在内质网中的细胞稳态和蛋白质加工的质量控制机制中的核心作用。

种属

Human

表达系统

HEK293

标签

C-6*His

蛋白编号

O95881 (H27-L168)

基因 ID
蛋白结构
N-term
TXNDC12 (H27-L168)
Accession # O95881
6*His
C-term
同用名
Thioredoxin Domain-Containing Protein 12; Endoplasmic Reticulum Resident Protein 18; ER Protein 18; ERp18; Endoplasmic Reticulum Resident Protein 19; ER Protein 19; ERp19; Thioredoxin-Like Protein p19; hTLP19; TXNDC12; TLP19
氨基酸序列

HNGLGKGFGDHIHWRTLEDGKKEAAASGLPLMVIIHKSWCGACKALKPKFAESTEISELSHNFVMVNLEDEEEPKDEDFSPDGGYIPRILFLDPSGKVHPEIINENGNPSYKYFYVSAEQVVQGMKEAQERLTGDAFRKKHL

分子量

Approximately 18.0 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

TXNDC12 Protein, Human (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
TXNDC12 Protein, Human (HEK293, His)
目录号:
HY-P71046
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