2. Peptides
  3. Substance P(1-4)

Substance P(1-4) 是一种有效的神经激肽受体(NK-R)拮抗剂。Substance P(1-4) 对正常造血有调节作用，抑制内源性红细胞集落 (EEC) 的形成。

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Substance P(1-4) Chemical Structure

Substance P(1-4) Chemical Structure

CAS No. : 57468-16-3

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Substance P(1-4) 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Substance P(1-4) is a potent neurokinin receptors (NK-R) antagonist. Substance P(1-4) has regulation of normal hematopoiesis and inhibits endogenous erythroid colony (EEC) formation[1].

体外研究
(In Vitro)

Substance P(1-4) (0.1 nM-1 μM) inhibits endogenous erythroid colony (EEC) formation in PV bone marrow cultures[1].
Substance P(1-4) (0.1 nM-1 μM; CD36+/GpA- cells) decreases of erythroid colony numbers of 47% and inhibits proliferation of PV CD36+/GpA- cells of 30 %[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Substance P(1-4) 相关抗体:

Cell Viability Assay[1]

Cell Line: PV CD36+/GpA- cells
Concentration: 0.1 nM-1 μM
Incubation Time: 2 days
Result: Inhibited proliferation of PV CD36+/GpA- cells of 30 %.

Apoptosis Analysis[1]

Cell Line: PV CD36+/GpA- cells
Concentration: 10 nM
Incubation Time: 2 days
Result: Increased the percentage of cell death of 27.3%.
分子量

496.60

Formula

C22H40N8O5
CAS 号
Sequence Shortening

RPKP
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

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  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Substance P(1-4)57468-16-3Othersnormal hematopoiesisendogenous erythroid colonyCD36+/GpA- cellsInhibitorinhibitorinhibit

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目录号：
HY-P3598
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