2. Inhibitory Antibodies
  3. Tanezumab

Tanezumab  (Synonyms: RN-624; PF 4383119)

目录号: HY-P99221 纯度: 99.52%
COA

摩尔计算器

Tanezumab (RN-624) 是一种具有高亲和力和特异性的人源化抗 NGF 单克隆抗体，能阻断 NGF 与周围神经系统中的受体 p75 和 TrkA 结合。Tanezumab 可用于急性和慢性疼痛，如骨关节炎，膝关节和神经痛和带状疱疹后神经痛的研究。

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Tanezumab Chemical Structure

Tanezumab Chemical Structure

CAS No. : 880266-57-9

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规格 价格 是否有货 数量
1 mg ￥2100
In-stock
5 mg ￥5250
In-stock
10 mg ￥8400
In-stock
50 mg   询价  
100 mg   询价  

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Customer Review

Tanezumab 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Tanezumab (RN-624) is a humanized anti-NGF mAb with high affinity and specificity. Tanezumab blocks NGF binding to its receptors, p75 and TrkA, in the peripheral nervous system. Tanezumab can be used in studies of acute and chronic pain such as osteoarthritis, knee and neuralgia, as well as post-herpetic neuralgia[1][2].

同型

Human IgG2 kappa
推荐同型对照抗体
种属

Humanized
IC50 & Target

NGF[1][2].
Clinical Trial
CAS 号
性状

液体

颜色

Colorless to light yellow

运输条件

Shipping with dry ice.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

纯度: 99.52%

COA (150 KB)

抗体抑制剂使用指南 (1152 KB)
参考文献

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tanezumab880266-57-9RN-624 PF 4383119RN624RN 624PF4383119PF 4383119PF-4383119Otherspostherpetic neuralgiaPHNacute painchronic painosteoarthritisInhibitorinhibitorinhibit

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