1. PROTAC
  2. Ligands for E3 Ligase
  3. Thalidomide-5-NH-PEG5-NH2 hydrochloride

Thalidomide-5-NH-PEG5-NH2 hydrochloride 

目录号: HY-156170
产品使用指南

Thalidomide-5-NH-PEG5-NH2 hydrochloride 是一种基于 Thalidomide (HY-14658) 的,可募集 CRBN 蛋白的 cereblon 配体。Thalidomide-5-NH-PEG5-NH2 hydrochloride 可通过 linker 与靶蛋白配体连接,形成 PROTAC 分子。例如 THAL-SNS-032 (HY-123937)。

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Thalidomide-5-NH-PEG5-NH2 hydrochloride Chemical Structure

Thalidomide-5-NH-PEG5-NH2 hydrochloride Chemical Structure

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查看 Ligands for E3 Ligase 亚型特异性产品:

  • 生物活性

  • 纯度 & 产品资料

生物活性

Thalidomide-5-NH-PEG5-NH2 hydrochloride is the Thalidomide (HY-10984)-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-NH-PEG5-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs[1].

分子量

573.04

Formula

C25H37ClN4O9

性状

油状物

颜色

Light yellow to green yellow

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

纯度 & 产品资料

Thalidomide-5-NH-PEG5-NH2 hydrochloride 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Thalidomide-5-NH-PEG5-NH2 hydrochloride
目录号:
HY-156170
需求量: