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  3. [Thr28, Nle31]-Cholecystokinin (25-33), sulfated

[Thr28, Nle31]-Cholecystokinin (25-33), sulfated 

目录号: HY-P5519
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摩尔计算器

[Thr28, Nle31]-Cholecystokinin (25-33) 是一种有生物活性的肽。(胆囊收缩素 (CCK) 既充当激素又充当神经递质，存在于胃肠道系统和中枢神经系统中。它是一种抑制食物摄入的饱腹感肽。这种胆囊收缩素 (CCK) 类似物保留了 CCK8 的所有生物活性，但发现在酸性介质中更加稳定，并且由于 Met 替代（Thr 28 和 Nle31 被替代）而不受空气氧化的影响蛋氨酸）。主要构象包含以 Thr4 为中心的 γ 转角，由 Gly5 与包含 C 端残基的螺旋片段隔开。)

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[Thr28, Nle31]-Cholecystokinin (25-33), sulfated Chemical Structure

[Thr28, Nle31]-Cholecystokinin (25-33), sulfated Chemical Structure

CAS No. : 77568-41-3

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[Thr28, Nle31]-Cholecystokinin (25-33), sulfated 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

生物活性

[Thr28, Nle31]-Cholecystokinin (25-33) is a biological active peptide. (Cholecystokinin (CCK) acts both as a hormone and a neurotransmitter and is found in the GI system and the central nervous system. It is a satiety peptide that inhibits food intake.This Cholecystokinin (CCK) analog retains all the bioactivities of CCK8, but was found to be remarkably more stable in acidic media and unaffected by air oxidation due to Met replacements (Thr 28 and Nle31 were substituted for Methionine). The predominant conformation contains a gamma-turn centered on Thr4, separated by Gly5 from a helical segment that comprises the C-terminal residues.)

分子量

1251.32

Formula

C55H74N14O18S
CAS 号
Sequence

Arg-Asp-{Tyr(SO3H)}-Thr-Gly-Trp-{Nle}-Asp-Phe-NH2
Sequence Shortening

RD-{Tyr(SO3H)}-TGW-{Nle}-DF-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料

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  • 稀释计算器

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

[Thr28, Nle31]-Cholecystokinin (25-33), sulfated77568-41-3OthersInhibitorinhibitorinhibit

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