2. Protein Tyrosine Kinase/RTK
  3. Anaplastic lymphoma kinase (ALK)
  4. TL13-22

TL13-22 是 一种 TL13-12 (HY-122582) 的阴性对照，是一种有效的 ALK 抑制剂，IC50 为 0.54 nM。TL13-22 不会降解细胞中的 ALK。

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TL13-22 Chemical Structure

TL13-22 Chemical Structure

CAS No. : 2229036-65-9

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规格 价格 是否有货 数量
5 mg ￥8986
3 - 4 周
10 mg   询价  
50 mg   询价  

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TL13-22 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

TL13-22 is a negative control for TL13-12 (HY-122582) and a potent ALK inhibitor with an IC50 of 0.54 nM. TL13-22 does not degrade ALK in cells[1].

IC50 & Target

IC50: 0.54 nM (ALK)[1]
体外研究
(In Vitro)

TL13-22 prompts the degradation of additional kinases including Aurora A, FER, PTK2, and RPS6KA1 with IC50 values of 11.3 nM, 5.74 nM, 18.4 nM, and 65.9 nM, respectively[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

TL13-22 相关抗体:
分子量

947.50

Formula

C45H55ClN10O9S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

TL13-22 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TL13-222229036-65-9Anaplastic lymphoma kinase (ALK)Anaplastic lymphoma kinaseALK tyrosine kinase receptorCD246Cluster of differentiation 246TL13-12negativecontrolAurora AFERPTK2RPS6KA1Inhibitorinhibitorinhibit

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产品名称：
TL13-22
目录号：
HY-136194
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