2. Membrane Transporter/Ion Channel
  3. ATP Synthase
  4. Triciribine phosphate

Triciribine phosphate  (Synonyms: TCN-P)

目录号: HY-10250
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摩尔计算器

Triciribine phosphate (TCN-P) 通过变构机制抑制酰胺磷酸核糖基转移酶，影响嘌呤从头生物合成的第一个关键步骤。Triciribine phosphate 还抑制 IMP 脱氢酶，这是鸟苷核苷酸合成的第一个关键步骤。Triciribine phosphate 不影响连接酶活性。

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Triciribine phosphate Chemical Structure

Triciribine phosphate Chemical Structure

CAS No. : 61966-08-3

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Triciribine phosphate 的其他形式现货产品:

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Other Forms of Triciribine phosphate:

Triciribine phosphate 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Triciribine phosphate (TCN-P) inhibits amidophosphoribosyltransferase by an allosteric mechanism which affects the first committed step of de novo purine biosynthesis. Triciribine phosphate also inhibits  IMP dehydrogenase which is the first committed step of guanosine nucleotide synthesis. Tricilibine phosphate does not affect ligase activity[1].

分子量

400.28

Formula

C13H17N6O7P
CAS 号
性状

固体

颜色

Light yellow to yellow

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

纯度 & 产品资料

纯度: ≥99.0%

COA (197 KB)

产品使用指南 (1538 KB)
参考文献

Triciribine phosphate 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Triciribine61966-08-3TCN-PATP SynthaseAmidophosphoribosyltransferase InhibitorIMP dehydrogenase InhibitorInhibitorinhibitorinhibit

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