2. Immunology/Inflammation
  3. COX
  4. Valeryl salicylate

Valeryl salicylate  (Synonyms: Valeroyl salicylate)

目录号: HY-128473 纯度: ≥99.0%
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摩尔计算器

Valeryl salicylate 是一种有效且不可逆的 cyclooxygenase-1 (COX-1) 抑制剂。Valeryl salicylate 具有抗炎作用。

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Valeryl salicylate Chemical Structure

Valeryl salicylate Chemical Structure

CAS No. : 64206-54-8

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规格 价格 是否有货 数量
5 mg ￥300
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10 mg ￥450
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Valeryl salicylate 相关抗体

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COX COX-1 COX-2 COX-3

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Valeryl salicylate is a potent and irreversible cyclooxygenase-1 (COX-1) inhibitor. Valeryl salicylate shows anti-inflammatory effect[1].

IC50 & Target[1]

COX-1

 

体内研究
(In Vivo)

Valeryl salicylate (3, 10, 30 mg/kg; i.p.) 对花生四烯酸 (HY-109590) 引起的耳水肿和角叉菜胶 (HY-125474) 引起的爪水肿具有抗炎作用[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 25-30g, Swiss male mice (arachidonic acid induces Ear oedema)[1]
Dosage: 1.5, 4.5, 15, 45 μg per ear
Administration:
Result: Showed the anti-inflammatory effect of topical administration and resulted in significant inhibition of the ear oedema of28, 36, 40, and 58% at 1.5, 4.5, 15, 45 μg per ear.
Animal Model: 25-30g, Swiss male mice (Carrageenan-induced paw oedema)[1]
Dosage: 3, 10, 30 mg/kg
Administration: I.p.
Result: Promoted a significant inhibition of 43.3, 53.3 and 66.6% at 3, 10, 30 mg/kg, respectively.
分子量

222.24

Formula

C12H14O4
CAS 号
性状

固体

颜色

White to off-white

中文名称

戊酰基水杨酸； 水杨酸戊酯
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
纯度 & 产品资料

纯度: ≥99.0%

COA (169 KB)

产品使用指南 (1538 KB)
参考文献

Valeryl salicylate 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Valeryl64206-54-8Valeroyl戊酰基水杨酸 水杨酸戊酯COXCyclooxygenaseanti-inflammatoryarachidonic acidCarrageenanoedemaInhibitorinhibitorinhibit

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目录号：
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