2. Cell Cycle/DNA Damage Stem Cell/Wnt Cytoskeleton TGF-beta/Smad
  3. ROCK
  4. Y-33075 hydrochloride

Y-33075 hydrochloride  (Synonyms: Y-39983)

目录号: HY-10068
产品使用指南

摩尔计算器

Y-33075 hydrochloride (Y-39983) 是选择性ROCK抑制剂，由 Y-27632 衍生而来,，IC50 为 3.6 nM，比 Y-27632 更有效。

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Y-33075 hydrochloride Chemical Structure

Y-33075 hydrochloride Chemical Structure

CAS No. : 471843-75-1

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Y-33075 hydrochloride 的其他形式现货产品:

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Y-33075 hydrochloride 相关抗体

Top Publications Citing Use of Products

    Y-33075 hydrochloride purchased from MCE. Usage Cited in: PLoS One. 2023 Jan 31;18(1):e0270288.  [Abstract]

    Y-27632 (10, 100 nM and 10, 100 µM; 24 h) decreases phosphorylation of MLC starting at a concentration of 100 nM in HSCs.

    Y-33075 hydrochloride purchased from MCE. Usage Cited in: Neurotox Res. 2013 Apr;23(3):238-48.  [Abstract]

    Effect of Y39983 on glutamate-treated HT22 cell viability.

    查看 ROCK 亚型特异性产品:

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    ROCK ROCK1 ROCK2

    • 生物活性

    • 纯度 & 产品资料

    • 参考文献

    生物活性

    Y-33075 hydrochloride (Y-39983) is a selective ROCK inhibitor derived from Y-27632, and is more potent than Y-27632, with an IC50 of 3.6 nM.

    体外研究
    (In Vitro)

    Y-33075 hydrochloride (Y-39983, 10 μM) 与未经Y-39983 处理的 RGCs 相比，延长了视网膜神经节细胞 (RGCs) 的神经突[2]。Y-33075 hydrochloride (Y-39983, 1 μM) 抑制组胺在Ca2+无溶液中引起的兔纤毛动脉段收缩。Y-33075 hydrochloride (10 μM) 对 Ca2+ 没有影响，随着高钾 (高 k) 溶液的加入而增加[3]。

    MCE has not independently confirmed the accuracy of these methods. They are for reference only.

    Y-33075 hydrochloride 相关抗体:
    分子量

    316.79

    Formula

    C16H17ClN4O
    CAS 号
    运输条件

    Room temperature in continental US; may vary elsewhere.
    储存方式

    Please store the product under the recommended conditions in the Certificate of Analysis.
    纯度 & 产品资料
    参考文献

    Y-33075 hydrochloride 相关分类

    • 摩尔计算器

    • 稀释计算器

    The molarity calculator equation

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    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    Y-33075471843-75-1Y-39983Y33075Y 33075Y39983Y 39983ROCKRho-associated protein kinaseRho-associated kinaseRho-kinaseROKROCK?InhibitorRGCretinal ganglion celloptic nerveInhibitorinhibitorinhibit

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