2. GPCR/G Protein Neuronal Signaling Immunology/Inflammation
  3. Histamine Receptor
  4. Zolantidine dimaleate

Zolantidine dimaleate  (Synonyms: SKF 95282 dimaleate)

目录号: HY-101373A 纯度: 99.88%
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摩尔计算器

Zolantidine dimaleate (SKF 95282 dimaleate) 是一种有效的、选择性的、可穿过血脑屏障的 histamine H2 拮抗剂。Zolantidine dimaleate 诱导镇痛作用。

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Zolantidine dimaleate Chemical Structure

Zolantidine dimaleate Chemical Structure

CAS No. : 104076-39-3

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Zolantidine dimaleate 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

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生物活性

Zolantidine dimaleate (SKF 95282 dimaleate) is a potent, selective and cross the blood-brain barrier histamine H2 antagonist. Zolantidine dimaleate induces antinociception[1][2].

IC50 & Target[1]

H2 Receptor

 

体内研究
(In Vivo)

Zolantidine dimaleate (5、10、20、40 mg/kg；皮下注射) 在胆汁淤积大鼠中诱导抗伤害作用[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 200-250 g, male Wistar rats (cholestatic rats)[2]
Dosage: 5, 10, 20, 40 mg/kg
Administration: S.c.
Result: Significantly increased tail-flick latencies and induced antinociception.
分子量

613.68

Formula

C30H35N3O9S
CAS 号
性状

固体

颜色

White to off-white

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

纯度 & 产品资料
参考文献

Zolantidine dimaleate 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

Zolantidine dimaleate104076-39-3SKF 95282 dimaleateHistamine ReceptorInhibitorinhibitorinhibit

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目录号：
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