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  4. (1R,3S)-RSL3

(1R,3S)-RSL3 是 RSL3 ((1S,3R)-RSL3) 的活性较低的 (1R,3S)-对映体。(1R,3S)-RSL3 和 RSL3 诱导 HT22 野生型细胞死亡，EC50 值分别为 5.2 µM 和 0.004 µM。

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(1R,3S)-RSL3 Chemical Structure

(1R,3S)-RSL3 Chemical Structure

CAS No. : 1219810-13-5

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Other Forms of (1R,3S)-RSL3:

(1R,3S)-RSL3 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

(1R,3S)-RSL3 is the less active (1R,3S)-enantiomer of RSL3 ((1S,3R)-RSL3). (1R,3S)-RSL3 and RSL3 induce cell death in HT22 wild-type cells with EC50 values of 5.2 µM and 0.004 µM, rspectively[1].

体外研究
(In Vitro)

(1R,3S)-RSL3（0.1 nM-100 µM；16 小时）诱导 HT22 野生型 (WT) 和 HT22 Bid CRISPR KO 细胞死亡，EC50 值分别为 5.2 µM 和 28.8 µM[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

(1R,3S)-RSL3 相关抗体:

Cell Viability Assay[1]

Cell Line: HT22 WT and HT22 Bid CRISPR KO cells
Concentration: 0.1 nM-100 µM
Incubation Time: 16 h
Result: Inhibited cells growth.
分子量

440.88

Formula

C23H21ClN2O5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

(1R,3S)-RSL3 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(1R,3S)-RSL31219810-13-5Others(1R,3S)-enantiomerInhibitorinhibitorinhibit

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