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AWZ1066S 

目录号: HY-114415 纯度: 98.65% ee.: 99.67%
产品使用指南

AWZ1066S 是一种高度特异性的抗 Wolbachia 的候选药物,可于用丝虫病的短期治疗,其在细胞中测得的 EC50 值为 2.5 nM。

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AWZ1066S Chemical Structure

AWZ1066S Chemical Structure

CAS No. : 2239272-16-1

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Size Price Stock Quantity
10 mM * 1 mL in DMSO ¥385 In-stock
5 mg ¥3500 In-stock
10 mg ¥5500 In-stock
50 mg ¥19500 In-stock
100 mg ¥29500 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

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Description

AWZ1066S is a highly specific anti-Wolbachia drug candidate for a short-course treatment of filariasis, with an EC50 of 2.5 nM in cell assay[1].

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (309.11 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.4729 mL 12.3643 mL 24.7286 mL
5 mM 0.4946 mL 2.4729 mL 4.9457 mL
10 mM 0.2473 mL 1.2364 mL 2.4729 mL
*请根据产品在不同溶剂中的溶解度,选择合适的溶剂配制储备液。
In Vivo:
  • 1.

    请依序添加每种溶剂: 10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (5.14 mM); Clear solution

  • 2.

    请依序添加每种溶剂: 10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (5.14 mM); Clear solution

  • 3.

    请依序添加每种溶剂: 10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (5.14 mM); Clear solution

*以上所有助溶剂都可在 MCE 网站选购。
References
Molecular Weight

404.39

Formula

C₁₉H₁₉F₃N₆O

CAS No.

2239272-16-1

SMILES

C[C@@H](COCC1)N1C2=NC3=C(C=CC=N3)C(NCC4=CC=CN=C4C(F)(F)F)=N2

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
AWZ1066S
目录号:
HY-114415
需求量:

AWZ1066S

Cat. No.: HY-114415