1. Immunology/Inflammation
  2. Toll-like Receptor (TLR)
  3. IAXO-102

IAXO-102 

目录号: HY-125171
产品使用指南

IAXO-102 是 TLR4 的拮抗剂,抑制 MAPK 和 p65 NF-kB 的磷酸化,这些与 TLR4 和 TLR4 依赖性的炎性蛋白的表达下调有关。IAXO-102 抑制实验性腹主动脉瘤的发展。

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IAXO-102 Chemical Structure

IAXO-102 Chemical Structure

CAS No. : 1115270-63-7

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Description

IAXO-102 is a TLR4 antagonist, inhibits MAPK and p65 NF-kB phosphorylation involved in down regulation of the expression of TLR4 and TLR4 dependent proinflammatory protein. IAXO-102 prevents experimental abdominal aortic aneurysm development[1].

IC50 & Target[1]

TLR4

 

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
Molecular Weight

585.94

Formula

C₃₅H₇₁NO₅

CAS No.

1115270-63-7

SMILES

CCCCCCCCCCCCCCO[C@@H]1[C@H]([C@@H]([C@@H](CN)O[C@@H]1OC)O)OCCCCCCCCCCCCCC

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Room temperature in continental US; may vary elsewhere

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
IAXO-102
目录号:
HY-125171
需求量:

IAXO-102

Cat. No.: HY-125171