1. Metabolic Enzyme/Protease
  2. Carbonic Anhydrase

Indisulam (Synonyms: E 7070)

目录号: HY-13650 纯度: 98.92%
产品使用指南

Indisulam (E 7070) 是一种 碳酸酐酶抑制剂,也是细胞周期G1期的靶向化合物。通过抑制细胞周期蛋白依赖型激酶 2 (CDK2) 和周期蛋白 E (cyclin E) 的激活,导致G1/S转化被阻滞。在人结肠癌和肺癌细胞中显示了抗肿瘤活性。

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Indisulam Chemical Structure

Indisulam Chemical Structure

CAS No. : 165668-41-7

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Size Price Stock Quantity
10 mM * 1 mL in DMSO ¥1210 In-stock
5 mg ¥1100 In-stock
10 mg ¥1900 In-stock
25 mg ¥4100 In-stock
50 mg ¥7200 In-stock
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Description

Indisulam (E 7070) is a carbonic anhydrase inhibitor and a G1-targeting agent. Indisulam causes a blockade in the G1/S transition through inhibition of the activation of both cyclin-dependent kinase 2 (CDK2) and cyclin E. Shows anti-tumor activity in human colon and lung cancer cells[1][2].

IC50 & Target

Carbonic anhydrase[1].

References
Molecular Weight

385.85

Formula

C₁₄H₁₂ClN₃O₄S₂

CAS No.

165668-41-7

SMILES

O=S(C1=CC=C(S(=O)(N)=O)C=C1)(NC2=CC=CC3=C2NC=C3Cl)=O

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
Indisulam
目录号:
HY-13650
需求量:

Indisulam

Cat. No.: HY-13650