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Anticancer agent 103 (Compound 2k) 是一种有效的抗癌剂。

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Anticancer agent 103 Chemical Structure

Anticancer agent 103 Chemical Structure

CAS No. : 2914922-78-2

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Anticancer agent 103 (Compound 2k) is a potent anticancer agent[1].

体外研究
(In Vitro)

Anticancer agent 103 (Compound 2k; 12.5-400 μM; 24 or 48 h) 抑制 HepG2 细胞活力,但不抑制 Colo-205 细胞活力[1]
Anticancer agent 103 (25 and 50 μM; 24 h) 增加 HepG2 细胞中 FoXO1、TXNIP 和 p27 蛋白水平[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay[1]

Cell Line: HepG2 and Colo-205 cells
Concentration: 12.5, 25, 50, 100, 200 and 400 μM
Incubation Time: 24 or 48 h
Result: Demonstrated anticancer activity against cancer cell line HepG2 with IC50s of 30.5 μM and 14.8 μM for 24h and 48 h, respectively. The IC50 for Colo-205 was >400 μM.

Western Blot Analysis[1]

Cell Line: HepG2 cells
Concentration: 25 and 50 μM
Incubation Time: 24 h
Result: Increased the FoXO1, TXNIP and p27 protein levels.
分子量

374.27

Formula

C18H20BrN3O

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

Anticancer agent 103 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Anticancer agent 103
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HY-149216
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