2. PROTAC Anti-infection
  3. PROTACs Bacterial
  4. BacPROTAC-1

BacPROTAC-1 是一个 mSA BacPROTAC 降解剂。BacPROTAC-1 对 mSA 和 ClpCNTD 具有高亲和力 (KD 分别为 3.9 μM 和 2.8 μM)。

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BacPROTAC-1 Chemical Structure

BacPROTAC-1 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
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BacPROTAC-1 相关抗体

Top Publications Citing Use of Products

查看 PROTACs 亚型特异性产品:

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von Hippel-Lindau (VHL) Cereblon MDM2 cIAP1

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

BacPROTAC-1 is a mSA BacPROTAC degrader. BacPROTAC-1 binds mSA and ClpCNTD with high affinity (KDs of 3.9 and 2.8 μM, respectively)[1].

IC50 & Target

KD: 2.8 μM (ClpCNTD), 3.9 μM (mSA)[1]
体外研究
(In Vitro)

mSA 单独和 mSA 融合蛋白 (mSA-NrdI、mSA-TagD、mSA-NusA、mSA-Kre) 被 ClpCP 以依赖 BacPROTAC-1 的方式降解 (1-100 μM; 2 h)。这种降解是 ATP 依赖的，pArg 或生物素阻断 BacPROTAC-1 诱导的降解[1]。
BacPROTAC-1 诱导活性 ClpC 寡聚物[1]。
BacPROTAC-1 (1-100 μM) 可以重编程分枝杆菌 ClpC1P1P2[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

BacPROTAC-1 相关抗体:
分子量

1127.25

Formula

C45H83N12O17PS
Unlabeled Cas

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

BacPROTAC-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

BacPROTAC-1BacPROTAC1BacPROTAC 1PROTACsBacterialmSA-NrdImSA-TagDmSA-NusAmSA-KremycobacterialInhibitorinhibitorinhibit

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产品名称：
BacPROTAC-1
目录号：
HY-153575
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