2. Others Neuronal Signaling
  3. Isotope-Labeled Compounds Calcineurin
  4. Cyclosporin A-13C2,d4

Cyclosporin A-13C2,d4  (Synonyms: 环孢素-13C2,d4; Cyclosporine A-13C2,d4; Ciclosporin A-13C2,d4; CsA-13C2,d4)

目录号: HY-B0579S3
产品使用指南

摩尔计算器

Cyclosporin A-13C2,d4 (Cyclosporine A-13C2,d4; Ciclosporin A-13C2,d4) 是一种 13C 标记的 Cyclosporin A (HY-B0579)。Cyclosporin A (Cyclosporine A) 是一种免疫抑制剂，能与亲环素结合，抑制 protein phosphatase 2B (PP2B/calcineurin) 活性的IC50 值为 7 nM。Cyclosporin A 也抑制 CD11a/CD18 粘附分子。

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Cyclosporin A-<sup>13</sup>C<sub>2</sub>,d<sub>4</sub> Chemical Structure

Cyclosporin A-13C2,d4 Chemical Structure

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规格 价格 是否有货
500 μg ￥14600
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Other Forms of Cyclosporin A-13C2,d4:

Cyclosporin A-13C2,d4 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Cyclosporin A-13C2,d4 (Cyclosporine A-13C2,d4; Ciclosporin A-13C2,d4) is a 13C labeled Cyclosporin A (HY-B0579)[1]. Cyclosporin A (Cyclosporine A) is an immunosuppressant which binds to the cyclophilin and inhibits phosphatase activity of protein phosphatase 2B (PP2B/calcineurin) with an IC50 of 5 nM[2]. Cyclosporin A also inhibits CD11a/CD18 adhesion[3].

体外研究
(In Vitro)

氢、碳和其他元素的稳定重同位素已被纳入药物分子中，主要作为药物开发过程中定量的示踪剂。氘化引起了人们的关注，因为它可能影响药物的药代动力学和代谢谱[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Cyclosporin A-13C2,d4 相关抗体:
分子量

1208.62

Formula

C6013C2H107D4N11O12
中文名称

环孢霉素A-13C2,d4；环孢素A-13C2,d4；环孢多肽A-13C2,d4；环孢灵-13C2,d4；赛斯平-13C2,d4；环孢素-13C2,d4
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Cyclosporin A-13C2,d4 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Cyclosporin A-13C2,d4Cyclosporine A-13C2,d4 Ciclosporin A-13C2,d4 CsA-13C2,d4环孢霉素A-13C2,d4环孢素A-13C2,d4环孢多肽A-13C2,d4环孢灵-13C2,d4赛斯平-13C2,d4环孢素-13C2,d4Isotope-Labeled CompoundsCalcineurinPP2BPPP3Inhibitorinhibitorinhibit

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