2. Membrane Transporter/Ion Channel Neuronal Signaling
  3. nAChR
  4. Dihydro-β-erythroidine

Dihydro-β-erythroidine 是一种竞争性烟碱受体 (nicotinic receptor) 拮抗剂。Dihydro-β-erythroidine 可阻断尼古丁的辨别刺激特性。Dihydro-β-erythroidine 抑制尼古丁诱导的抗焦虑作用。

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Dihydro-β-erythroidine Chemical Structure

Dihydro-β-erythroidine Chemical Structure

CAS No. : 23255-54-1

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Dihydro-β-erythroidine 的其他形式现货产品:

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Dihydro-β-erythroidine 相关抗体

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MCE 顾客使用本产品发表的 1 篇科研文献

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Dihydro-β-erythroidine is a a competitive nicotinic receptor antagonist. Dihydro-β-erythroidine blocks the discriminative stimulus properties of nicotine. Dihydro-β-erythroidine inhibits the anxiolytic effect of nicotine induced[1][2].

体内研究
(In Vivo)

Dihydro-β-erythroidine (0.5, 1.6, 5.0 mg/kg; s.c.) blocks the discriminative stimulus properties of nicotine in rats[1].
Dihydro-β-erythroidine (100 ng) shows antagonism of the anxiolytic effect of nicotine in the dorsal raphe´ nucleus in rats[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 200-250 g male hooded Lister rats[1]
Dosage: 0.5, 1.6, 5.0 mg/kg
Administration: S.c.
Result: Prevented the development of CTAs (conditioned taste aversion) and blocked the discriminative stimulus effect of nicotine (0.2 or 0.4 mg/kg SC) for 45 min after its administration.
分子量

275.34

Formula

C16H21NO3
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Dihydro-β-erythroidine 相关分类

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Keywords:

Dihydro-β-erythroidine23255-54-1nAChRNicotinic acetylcholine receptorsnicotineanxiolyticInhibitorinhibitorinhibit

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目录号：
HY-N10497
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