2. Gene
  3. Limk2 - LIM motif-containing protein kinase 2 Gene

Limk2 - LIM motif-containing protein kinase 2 Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

中文名称：含 LIM 基序的蛋白激酶 2

种属: Mus musculus

同用名: whe; Limk-2

基因 ID: 16886 | 基因类型: protein coding

关于 Limk2

Chromosome 11: 3,294,256-3,359,189 reverse strand.GRCm39:CM001004.3

This gene has 13 transcripts (splice variants), 205 orthologues, 23 paralogues and is associated with 31 phenotypes. Ubiquitous expression in placenta adult (RPKM 23.2), colon adult (RPKM 19.9) and 27 other tissues.

功能概要

该基因编码的蛋白可启动蛋白激酶活性。作用于多个过程的上游或内部，包括相机型眼睛的角膜发育；蛋白质磷酸化；和精子发生。位于顺式高尔基体网络和细胞核中。以多种结构表达，包括消化系统；中枢神经系统;泌尿生殖系统；淋巴系统腺体；和感觉器官。与人类 LIMK2（LIM 结构域激酶 2）同源。 [由基因组资源联盟提供，2022 年 4 月]

Enables protein kinase activity. Acts upstream of or within several processes, including cornea development in camera-type eye; protein phosphorylation; and spermatogenesis. Located in cis-Golgi network and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system gland; and sensory organ. Orthologous to human LIMK2 (LIM domain kinase 2). [provided by Alliance of Genome Resources, Apr 2022]

Limk2 基因产物(9)

mRNA Protein Name
NM_001402862.1 NP_001389791.1 LIM domain kinase 2 isoform g
NM_001402860.1 NP_001389789.1 LIM domain kinase 2 isoform 3
NM_001402861.1 NP_001389790.1 LIM domain kinase 2 isoform f
NM_010718.4 NP_034848.1 LIM domain kinase 2 isoform a
NM_173053.2 NP_774958.1 LIM domain kinase 2 isoform b
NM_001034030.2 NP_001029202.1 LIM domain kinase 2 isoform c
NM_001402864.1 NP_001389793.1 LIM domain kinase 2 isoform c
NM_001402863.1 NP_001389792.1 LIM domain kinase 2 isoform h
NM_001361623.1 NP_001348552.1 LIM domain kinase 2 isoform d

Limk2 蛋白结构

LIM

LIM: cl02475 (11 - 64)

LIM2_LIMK2

LIM2_LIMK2: cd09465 (66 - 124)

PDZ

PDZ: pfam00595 (151 - 235)

STKc_LIMK2

STKc_LIMK2: cd14222 (336 - 607)

  • 0
  • 100
  • 200
  • 300
  • 400
  • 500
  • 600
  • 638 a.a.
蛋白主名 其他名称

LIM domain kinase 2

LIM kinase 2

相关产品

Pre-clinical Phase
生物活性分子 (10)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-18305 BMS-5 Inhibitor 99.51% 否
HY-18304 BMS-3 Inhibitor 99.46% 否
HY-122630 TH-257 Inhibitor 98.01% 否
HY-19352 T56-LIMKi Inhibitor 99.07% 否
HY-148063 DB0614 98.80% 否
HY-151539 TH470 Inhibitor 99.57% 否
HY-137346 DD-03-156 99.63% 否
HY-120025 CRT0105950 Inhibitor 99.91% 否
HY-128062 LIMK1 inhibitor BMS-4 Inhibitor ≥99.0% 否
HY-14227 LIMK-IN-1 Inhibitor / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Limk2 NCBI NCBI:3985
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z