1. Gene
  2. Sstr5 - somatostatin receptor 5 Gene

Sstr5 - somatostatin receptor 5 Gene

中文名称:生长抑素受体 5

种属: Rattus norvegicus

同用名: Smstr5; Somato

基因 ID: 25354 | 基因类型: protein coding

关于 Sstr5

Primary_assembly 10: 14,506,868-14,512,946 reverse strand.mRatBN7.2:CM026983.1

This gene has 1 transcript (splice variant), 257 orthologues, 14 paralogues and is associated with 8 phenotypes.

功能概要

该基因编码的蛋白可启动生长抑素受体活性。参与腺苷酸环化酶抑制 G 蛋白偶联受体信号通路和细胞对糖皮质激素刺激的反应。位于细胞质和质膜中。该基因的人类直系同源物与双相情感障碍有关。与人类 SSTR5(生长抑素受体 5)同源。 [由基因组资源联盟提供,2022 年 4 月]

Enables Somatostatin Receptor activity. Involved in adenylate cyclase-inhibiting G protein-coupled receptor signaling pathway and cellular response to glucocorticoid stimulus. Located in cytoplasm and plasma membrane. Human ortholog(s) of this gene implicated in bipolar disorder. Orthologous to human SSTR5 (Somatostatin Receptor 5). [provided by Alliance of Genome Resources, Apr 2022]

Sstr5 基因产物(1)

mRNA Protein Name
NM_012882.2 NP_037014.2 somatostatin receptor type 5

Sstr5 蛋白结构

7tm_GPCRs

7tm_GPCRs: cl28897 (47 - 313)

7tm_GPCRs

7tm_GPCRs: cd14964 (72 - 93)

7tm_GPCRs

7tm_GPCRs: cd14964 (109 - 131)

7tm_GPCRs

7tm_GPCRs: cd14964 (154 - 170)

7tm_GPCRs

7tm_GPCRs: cd14964 (196 - 219)

7tm_GPCRs

7tm_GPCRs: cd14964 (245 - 267)

7tm_GPCRs

7tm_GPCRs: cd14964 (281 - 306)

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  • 362 a.a.
蛋白主名 其他名称

somatostatin receptor type 5

SS-5-R

SS5-R

SS5R

Somatostatin receptor subtype 5

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sstr5 NCBI NCBI:6755