2. GPCR/G Protein Neuronal Signaling
  3. Adrenergic Receptor
  4. Oxprenolol

Oxprenolol  (Synonyms: Ba 39089 free base)

目录号: HY-B1486A
产品使用指南

摩尔计算器

Oxprenolol (Ba 39089 free base) 是一种具有口服活性的 β-肾上腺素受体 (β-AR) 拮抗剂，Ki 为 7.10 nM。

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Oxprenolol Chemical Structure

Oxprenolol Chemical Structure

CAS No. : 6452-71-7

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Oxprenolol 的其他形式现货产品:

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Other Forms of Oxprenolol:

Oxprenolol 相关抗体

Top Publications Citing Use of Products

MCE 顾客使用本产品发表的 1 篇科研文献

查看 Adrenergic Receptor 亚型特异性产品:

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α adrenergic receptor β adrenergic receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Oxprenolol (Ba 39089 free base) is an orally bioavailable β-adrenergic receptor (β-AR) antagonist with a Ki of 7.10 nM in a radioligand binding assay using rat heart muscle[1].

IC50 & Target[1]

β-adrenoceptor

7.10 nM (Ki)

体外研究
(In Vitro)

Oxprenolol is lipophilic[3].
Oxprenolol shows permeability rate constant of 1.54 ± 1.54×10-3 cm/h across abdominal human skin[3].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Oxprenolol 相关抗体:
体内研究
(In Vivo)

Oxprenolol (200 mg/kg/day; p.o.; daily for 3 weeks) produces effective beta-blockade together with peak plasma drug levels within the normal clinical range[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male rats (230 to 300 g body wt) of the Wistar strain[2]
Dosage: 200 mg/kg
Administration: Administered orally; daily for 3 weeks
Result: This dosage produced effective beta-blockade.
分子量

265.35

Formula

C15H23NO3
CAS 号
中文名称

氧烯洛尔； 心得平
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Oxprenolol 相关分类

  • 摩尔计算器

  • 稀释计算器

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Oxprenolol6452-71-7Ba 39089氧烯洛尔 心得平Ba39089Ba-39089Adrenergic ReceptorBeta Receptorhypertensionlipophilicabdominal human skinInhibitorinhibitorinhibit

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