2. Metabolic Enzyme/Protease
  3. Cytochrome P450
  4. (±)14,15-Epoxyeicosatrienoic acid

(±)14,15-Epoxyeicosatrienoic acid  (Synonyms: (±)14(15)-EET)

目录号: HY-150084
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(±)14,15-Epoxyeicosatrienoic acid ((±)14(15)-EET) 是花生四烯酸的细胞色素 Cytochrome P450 的代谢物。而 CYP3A4 可能参与乳腺癌细胞生长，(±)14,15-Epoxyeicosatrienoic acid 可能通过 CYP3A4 影响的 STAT3 促进有丝分裂和贴壁依赖性克隆。(±)14,15-Epoxyeicosatrienoic acid 表现出 STAT3 依赖性的细胞生长促进，还可能参与驱动细胞生长的自分泌/旁分泌途径。

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(±)14,15-Epoxyeicosatrienoic acid Chemical Structure

(±)14,15-Epoxyeicosatrienoic acid Chemical Structure

CAS No. : 197508-62-6

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(±)14,15-Epoxyeicosatrienoic acid 相关抗体

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查看 Cytochrome P450 亚型特异性产品:

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CYP1 CYP2 CYP3 CYP4 CYP11 CYP17 Aromatase/CYP19A1 CYP26 CYP51 CYP2D6 CYP2C9 CYP2C19 CYP3A4 CYP17A1

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生物活性

(±)14,15-Epoxyeicosatrienoic acid ((±)14(15)-EET) is the Cytochrome P450 metabolite of arachidonic acid. While CYP3A4 may be involved in breast cancer cell growth, (±)14,15-Epoxyeicosatrienoic acid may promote mitosis and anchorage-dependent cloning through STAT3 affected by CYP3A4. (±)14,15-Epoxyeicosatrienoic acid exhibits STAT3-dependent cell growth promotion and may also participate in the autocrine/paracrine pathway that drives cell growth[1][2].

分子量

320.47

Formula

C20H32O3
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

(±)14,15-Epoxyeicosatrienoic acid 相关分类

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Keywords:

(±)14,15-Epoxyeicosatrienoic acid197508-62-6(±)14(15)-EETCytochrome P450CYPsInhibitorinhibitorinhibit

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