CRELD1 蛋白, Mouse (HEK293, His)

The CRELD1 protein is a member of the protein disulfide isomerase family and is actively involved in rearrangements of disulfide bonds that contribute to important cellular processes. Of particular note is the role of CRELD1 in promoting the localization of acetylcholine receptors (AChR) to the plasma membrane. CRELD1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived CRELD1 protein, expressed by HEK293 , with C-His labeled tag. The total length of CRELD1 Protein, Mouse (HEK293, His) is 362 a.a., with molecular weight of ~40-50 KDa.

CRELD1 蛋白被鉴定为蛋白质二硫键异构酶家族的成员，在细胞过程中发挥着重要作用。这种蛋白质与该家族的其他成员类似，参与二硫键重排。值得注意的是，CRELD1 被发现可以促进乙酰胆碱受体 (AChR) 定位到质膜。这一功能强调了 CRELD1 在关键细胞成分（尤其是乙酰胆碱受体）的组织和定位中的重要性，强调了它对细胞通讯和信号传导过程的潜在影响。

Measured by its ability to induce adhesion of ATDC5 mouse chondrogenic cells. The ED₅₀ for this effect is 0.5602 μg/mL, corresponding to a specific activity is 1785.077 units/mg.

Mouse

HEK293

C-6*His

Q91XD7 (Q30-E362)

171508  [NCBI]

QPSPPPHPSPRAEPHPCHTCRALVDNFNKGLERTIRDNFGGGNTAWEEEKLSKYKDSETRLVEVLEGVCSRSDFECHRLLELSEELVENWWFHRQQEAPDLFQWLCSDSLKLCCPSGTFGPSCLPCPGGTERPCGGYGQCEGEGTRGGSGHCDCQAGYGGEACGQCGLGYFEAERNSSHLVCSACFGPCARCTGPEESHCLQCKKGWALHHLKCVDIDECGTEQATCGADQFCVNTEGSYECRDCAKACLGCMGAGPGRCKKCSRGYQQVGSKCLDVDECETVVCPGENEKCENTEGGYRCVCAEGYRQEDGICVKEQVPESAGFFAEMTEDE

Approximately 40-50 kDa due to the glycosylation

Greater than 95% as determined by reducing SDS-PAGE

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.