SCGB1A1 蛋白, Mouse (His)

Uteroglobin/SCGB1A1 protein exhibits versatile binding, interacting with phosphatidylcholine, phosphatidylinositol, PCB, and weakly binding to progesterone. Acting as a potent phospholipase A2 inhibitor, its antiparallel homodimeric structure is held by disulfide linkages. While its reported interaction with LMBR1L is controversial, Uteroglobin's multifaceted binding underscores potential roles in cellular processes, including lipid metabolism and inflammation. SCGB1A1 Protein, Mouse (His) is the recombinant mouse-derived SCGB1A1 protein, expressed by E. coli, with N-6*His labeled tag. The total length of SCGB1A1 Protein, Mouse (His) is 75 a.a., with molecular weight of ~9 kDa.

子宫珠蛋白/SCGB1A1 蛋白具有多种结合能力，可与磷脂酰胆碱、磷脂酰肌醇、多氯联苯 (PCB) 相互作用，并与黄体酮结合较弱。此外，它还是磷脂酶 A2 的有效抑制剂。在结构上，子宫珠蛋白形成反向平行同二聚体，通过二硫键连接在一起。然而，所报道的与 LMBR1L 的相互作用仍然存在争议，强调需要进一步研究这种特定的分子关联。子宫珠蛋白的多方面结合特性强调了其在多种细胞过程中的潜在作用，包括脂质代谢和炎症反应。

Measured by the ability of the immobilized protein to support the adhesion of the A549 human lung carcinoma cells.The ED₅₀ for this effect is 1.531 μg/mL, corresponding to a specific activity is 653.17 units/mg.

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  Measured by the ability of the immobilized protein to support the adhesion of the A549 human lung carcinoma cells.The ED₅₀ for this effect is 1.531 μg/mL, corresponding to a specific activity is 653.17 units/mg.

Mouse

E. coli

N-6*His

Q06318 (D22-96F)

22287  [NCBI]

DICPGFLQVLEALLMESESGYVASLKPFNPGSDLQNAGTQLKRLVDTLPQETRINIMKLTEKILTSPLCKQDLRF

Approximately 9 kDa

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  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of 50 mM Tris-HCL, 300 mM NaCl, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.