Serpin E2 蛋白, Human (HEK293, His)

Serpin E2 is a serine protease inhibitor that inhibits thrombin, trypsin, and urokinase. Its unique role in promoting neurite extension involves specific inhibition of thrombin activity. Serpin E2 Protein, Human (HEK293, His) is the recombinant human-derived Serpin E2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of Serpin E2 Protein, Human (HEK293, His) is 378 a.a., with molecular weight of ~50.0 kDa.

Serpin E2 是一种丝氨酸蛋白酶抑制剂，对凝血酶、胰蛋白酶和尿激酶具有抑制活性。值得注意的是，它通过特异性抑制凝血酶活性来促进神经突延伸。通过与凝血酶的相互作用，丝氨酸蛋白酶抑制剂 E2 有助于调节参与各种细胞功能的蛋白水解过程。此外，该蛋白质表现出对肝素的结合亲和力，表明它参与与糖胺聚糖的相互作用，并可能在细胞信号传导或其他生物过程中调节其活性。

Human

HEK293

C-6*His

P07093-2 (S20-P397)

5270  [NCBI]

SHFNPLSLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGKILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEVRNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQPENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALPTESSTPLSAIIPHISTKTIDSWMSIMVPKRVQVILPKFTAVAQTDLKEPLKVLGITDMFDSSKANFAKITRSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP

Approximately 50.0 kDa

Greater than 95% as determined by reducing SDS-PAGE.

溶液.

Supplied as a 0.2 μm filtered solution of 20 mM Tris, 150 mM NaCl, pH 8.0.

<1 EU/μg, determined by LAL method.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.