2. Cell Cycle/DNA Damage Metabolic Enzyme/Protease
  3. DNA/RNA Synthesis Cytochrome P450
  4. S-(N-PhenethylthiocarbaMoyl)-L-cysteine

S-(N-PhenethylthiocarbaMoyl)-L-cysteine  (Synonyms: PEITC-Cys)

目录号: HY-115754
产品使用指南

摩尔计算器

S-(N-PhenethylthiocarbaMoyl)-L-cysteine (PEITC-Cys) 是一种抗癌物质 (anticarcinogenic)，具有抗白血病活性。S-(N-PhenethylthiocarbaMoyl)-L-cysteine 抑制 HL60 细胞的 DNA 合成。S-(N-PhenethylthiocarbaMoyl)-L-cysteine 是 P450 抑制剂。

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S-(N-PhenethylthiocarbaMoyl)-L-cysteine Chemical Structure

S-(N-PhenethylthiocarbaMoyl)-L-cysteine Chemical Structure

CAS No. : 53330-02-2

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S-(N-PhenethylthiocarbaMoyl)-L-cysteine 相关抗体

Top Publications Citing Use of Products

查看 Cytochrome P450 亚型特异性产品:

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CYP1 CYP2 CYP3 CYP4 CYP11 CYP17 Aromatase/CYP19A1 CYP26 CYP51 CYP2D6 CYP2C9 CYP2C19 CYP3A4 CYP17A1

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

S-(N-PhenethylthiocarbaMoyl)-L-cysteine (PEITC-Cys), an anticarcinogenic agent, has antileukemic activity. S-(N-PhenethylthiocarbaMoyl)-L-cysteine inhibits DNA synthesis in HL60 cells[1]. S-(N-PhenethylthiocarbaMoyl)-L-cysteine is a P450 inhibitor[2].

IC50 & Target

DNA Synthesis[1]; P450[2]
体外研究
(In Vitro)

S-(N-PhenethylthiocarbaMoyl)-L-cysteine inhibits cell growth of HL60 cell (GC50=336 nM)[1].
S-(N-PhenethylthiocarbaMoyl)-L-cysteine inhibits DNA synthesis in HL60 cells (IC50=6.47 μM)[1].
S-(N-PhenethylthiocarbaMoyl)-L-cysteine induced DNA fragmentation in HL 60 cells[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

S-(N-PhenethylthiocarbaMoyl)-L-cysteine 相关抗体:

Cell Proliferation Assay[1]

Cell Line: HL60 cells
Concentration: 0.1-10 μM
Incubation Time: 48 hours
Result: Inhibited the cell growth with a GC50 value of 336 nM.

Cell Proliferation Assay[1]

Cell Line: HL60 cells
Concentration: 4 μM
Incubation Time: 0, 20, 40, 60, 80, 100 hours
Result: Inhibited the cell growth.
分子量

284.40

Formula

C12H16N2O2S2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

S-(N-PhenethylthiocarbaMoyl)-L-cysteine 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

S-(N-PhenethylthiocarbaMoyl)-L-cysteine53330-02-2PEITC-CysDNA/RNA SynthesisCytochrome P450CYPsDNA fragmentationDNA synthesisHL60 cellcancerantileukemicInhibitorinhibitorinhibit

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