1. Cell Cycle/DNA Damage
  2. DNA Stain
  3. SiR-Hoechst

SiR-Hoechst 是一种远红荧光 DNA 探针,广泛用于活细胞的延时成像。 SiR-Hoechst 在浓度高达 10-25 µM 时毒性极小。 SiR-Hoechst 在浓度远低于 1 µM 时会诱导 DNA 损伤反应和 G2 停滞。

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SiR-Hoechst Chemical Structure

SiR-Hoechst Chemical Structure

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规格 是否有货
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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SiR-Hoechst is a far-red fluorescent DNA probe being used widely for time-lapse imaging of living cells. SiR-Hoechst is minimally toxic at concentrations as high as 10-25 µM. SiR-Hoechst induces DNA damage responses and G2 arrest at concentrations well below 1 µM[1][2].

体外研究
(In Vitro)

SiR-Hoechst 具有一些明显的优势:它对 DNA 具有选择性; DNA 结合后其荧光增强; 它由远红光激发,避免了传统 Hoechst 染料所需的紫外线造成的损害; 它与活细胞超分辨率显微镜兼容[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

950.21

Formula

C56H59N9O4Si

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

SiR-Hoechst 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
SiR-Hoechst
目录号:
HY-D2220
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