2. GPCR/G Protein Membrane Transporter/Ion Channel Neuronal Signaling
  3. 5-HT Receptor Monoamine Transporter
  4. FFN246

FFN246 是 serotonin transporter (SERT) 和 vesicular monoamine transporter 2 (VMAT2) 的荧光双底物探针，激发和发射光谱为 392/427 nm。FFN246 可以通过 SERT 依赖性积累来标记小鼠脑组织中的 5-羟色胺能神经元。

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FFN246 Chemical Structure

FFN246 Chemical Structure

CAS No. : 2210244-83-8

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FFN246 相关抗体

Top Publications Citing Use of Products

查看 5-HT Receptor 亚型特异性产品:

查看所有亚型
5-HT1 Receptor 5-HT2 Receptor 5-HT3 Receptor 5-HT4 Receptor 5-HT5 Receptor 5-HT6 Receptor 5-HT7 Receptor 5-HT Receptor

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

FFN246 is a fluorescent, dual substrate of serotonin transporter (SERT) probe and vesicular monoamine transporter 2 (VMAT2) with excitation and emission spectra 392/427 nm. FFN246 can be used for labeling serotonergic neurons in mouse brain tissue through SERT-dependent accumulation[1].

体内研究
(In Vivo)

FFN246 (2.5-20 μM, 30 mins) 可用于 96 孔板细胞培养实验中 5-羟色胺转运体(serotonin transporter, SERT) 活性和SERT 抑制剂的直接检测，也可用于急性小鼠脑片活体组织中缝背核 5-羟色胺能神经元的特异性标记[1]。
FFN246 (20 μM, 30 min) 可有效追踪 5-羟色胺能神经元体细胞中 5-羟色胺的摄取和包装[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
分子量

256.27

Formula

C15H13FN2O
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

FFN246 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FFN2462210244-83-8FFN 246FFN-2465-HT ReceptorMonoamine TransporterSerotonin Receptor5-hydroxytryptamine ReceptorImaging probeInhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-149170
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