1. PI3K/Akt/mTOR
  2. mTOR
  3. mTOR inhibitor-1

mTOR inhibitor-1 

目录号: HY-112914
产品使用指南

mTOR inhibitor-1是新颖的 mTOR 通路抑制剂,可抑制细胞增殖,诱导自噬。

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mTOR inhibitor-1 Chemical Structure

mTOR inhibitor-1 Chemical Structure

CAS No. : 468747-17-3

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     可免费申领三个不同产品的试用装。

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Size Price Stock Quantity
10 mM * 1 mL in DMSO ¥2750 In-stock
5 mg ¥2500 In-stock
10 mg ¥4500 In-stock
50 mg ¥14000 In-stock
100 mg ¥21000 In-stock
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

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Description

mTOR inhibitor-1 is a novel mTOR pathway inhibitor which can suppress cells proliferation and inducing autophagy.

IC50 & Target

mTOR[1]

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 83.33 mg/mL (229.43 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.7532 mL 13.7661 mL 27.5323 mL
5 mM 0.5506 mL 2.7532 mL 5.5065 mL
10 mM 0.2753 mL 1.3766 mL 2.7532 mL
*请根据产品在不同溶剂中的溶解度,选择合适的溶剂配制储备液。
In Vivo:
  • 1.

    请依序添加每种溶剂: 10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.08 mg/mL (5.73 mM); Clear solution

  • 2.

    请依序添加每种溶剂: 10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (5.73 mM); Clear solution

  • 3.

    请依序添加每种溶剂: 10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (5.73 mM); Clear solution

*以上所有助溶剂都可在 MCE 网站选购。
References
Molecular Weight

363.21

Formula

C₁₆H₁₅BrN₂O₃

CAS No.

468747-17-3

SMILES

O=C(N/N=C(C1=CC=C(O)C=C1O)\C)C2=CC=C(C)C(Br)=C2

Shipping

Room temperature in continental US; may vary elsewhere

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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产品名称:
mTOR inhibitor-1
目录号:
HY-112914
需求量:

mTOR inhibitor-1

Cat. No.: HY-112914