1. Epigenetics PI3K/Akt/mTOR NF-κB
  2. AMPK Keap1-Nrf2
  3. Fortunellin

Fortunellin  (Synonyms: 金柑苷)

目录号: HY-119678 纯度: 95.93%
COA 产品使用指南

Fortunellin 是一种黄酮类化合物,可以从金橘 (Fortunella margarita) 的果实中分离出来。Fortunellin 对小鼠的毒性很小,并能抑制 LPS 诱导的 H9C2 细胞炎症和 ROS 生成。Fortunellin 通过增强 AMPK/Nrf2 通路来防止果糖诱导的炎症和氧化应激。Fortunellin 可用于糖尿病心肌病研究。

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Fortunellin Chemical Structure

Fortunellin Chemical Structure

CAS No. : 20633-93-6

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1 mg ¥700
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5 mg ¥1250
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10 mg ¥2000
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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Fortunellin, is a flavonoid, that can be isolated from the fruits of Fortunella margarita (kumquat). Fortunellin exhibits little toxicity to mice and suppresses inflammation and ROS generation in H9C2 cells induced by LPS. Fortunellin protects against fructose-induced inflammation and oxidative stress by enhancing AMPK/Nrf2 pathway. Fortunellin can be used for diabetic cardiomyopathy research[1].

体外研究
(In Vitro)

Fortunellin 促进 AMPK 磷酸化,诱导 Nrf2 信号传导,通过上调 SOD、CAT 和 HO-1 作为抗氧化因子,从而显着减少氧化应激[2]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

592.55

Formula

C28H32O14

CAS 号
性状

固体

颜色

Off-white to light yellow

中文名称

金柑苷

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

纯度 & 产品资料
参考文献

Fortunellin 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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