2. Protein Tyrosine Kinase/RTK Immunology/Inflammation
  3. VEGFR PD-1/PD-L1
  4. Sotiburafusp alfa

Sotiburafusp alfa  (Synonyms: 索布瑞芙普α)

目录号: HY-P990088

摩尔计算器

Sotiburafusp alfa 是一种双特异性融合蛋白，是人源化的 VEGFR-1 胞外结构域片段通过肽连接体 101GGSGGSGGSGGSGGS115 融合到人源化的IgG1-kappa 抗 PD-L1 重链变体 L352>A、L353>A 的重链 N 端 (116-564)。Sotiburafusp alfa 也是一种血管生成抑制剂。

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Sotiburafusp alfa Chemical Structure

Sotiburafusp alfa Chemical Structure

CAS No. : 2637466-37-4

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Sotiburafusp alfa 相关抗体

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  • 生物活性

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  • 参考文献

生物活性

Sotiburafusp alfa is a bispecific fusion protein, which is a humanized VEGFR-1 extracellular domain fragment (129-228, 1-100 in the current sequence) fused via the peptide linker 101GGSGGSGGSGGSGGS115 to the N-terminus of the heavy chain (116-564) of a humanized IgG1-kappa anti-human PD-L1 heavy chain variant L352>A, L353>A. Sotiburafusp alfa is also an angiogenesis inhibitor[1].

CAS 号
中文名称

索布瑞芙普α
储存方式

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纯度 & 产品资料
参考文献

Sotiburafusp alfa 相关分类

  • 摩尔计算器

  • 稀释计算器

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  • Do most proteins show cross-species activity?

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Keywords:

Sotiburafusp alfa2637466-37-4索布瑞芙普αVEGFRPD-1/PD-L1Vascular endothelial growth factor receptorPD-1/Programmed death-ligand 1Inhibitorinhibitorinhibit

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