KIT - KIT proto-oncogene, receptor tyrosine kinase Gene

中文名称：K IT 原癌基因，受体酪氨酸激酶

种属: Macaca mulatta

基因 ID: 696759 | 基因类型: protein coding

关于 KIT

Primary_assembly 5: 78,894,923-78,984,329 reverse strand.Mmul_10:CM014340.1

This gene has 1 transcript (splice variant), 206 orthologues and 53 paralogues.

KIT 基因产物(1)

mRNA	Protein	Name
NM_001266095.1	NP_001253024.1	mast/stem cell growth factor receptor Kit precursor

KIT 蛋白结构

IgI_4_SCFR

PTKc_Kit

0
200
400
600
800
977 a.a.

蛋白主名

其他名称

mast/stem cell growth factor receptor Kit

Mast/stem cell growth factor receptor

重组 KIT 蛋白

目录号	产品名	蛋白编号	纯度
HY-P74336	CD117/c-kit Protein, Rhesus Macaque (HEK293, Fc)	NP_001253024.1 (Q26-T520)	≥95%

相关产品

Approval

生物活性分子 (28)

目录号	产品名	作用方式	纯度	是否罕见病
HY-10201	Sorafenib		99.92%	是
HY-10981	Lenvatinib	Inhibitor	99.84%	是
HY-16749	Pexidartinib		99.64%	是
HY-10331	Regorafenib		99.93%	是
HY-15463	Imatinib		99.95%	是
HY-13016	Cabozantinib		99.96%	是
HY-10230	Midostaurin		99.95%	是
HY-10208	Pazopanib		99.91%	是
HY-10201A	Sorafenib Tosylate		99.91%	是
HY-50946	Imatinib Mesylate		99.98%	是
HY-101561	Avapritinib	Inhibitor	99.94%	是
HY-10981A	Lenvatinib mesylate	Inhibitor	99.86%	是
HY-10209	Masitinib		99.98%	是
HY-112306	Ripretinib		99.33%	是
HY-16749A	Pexidartinib hydrochloride		99.86%	是
HY-12009	Pazopanib Hydrochloride		99.88%	是
HY-13308	Regorafenib Hydrochloride		99.58%	是
HY-10331A	Regorafenib monohydrate		99.96%	是
HY-12044	Cabozantinib S-malate		99.90%	是
HY-13904	Flumatinib	Inhibitor	99.94%	否
HY-10209A	Masitinib mesylate		99.83%	是
HY-13311A	Infigratinib phosphate	Inhibitor	99.74%	是
HY-10330A	Toceranib phosphate	Inhibitor	98.54%	否
HY-10330	Toceranib	Inhibitor	96.86%	否
HY-B1684	Mebrofenin		99.88%	否
HY-10331B	Regorafenib mesylate		/	否
HY-13016A	Cabozantinib hydrochloride		/	否
HY-50946R	Imatinib Mesylate (Standard)		/	否

Clinical Phase

生物活性分子 (28)

目录号	产品名	作用方式	纯度	Phase
HY-13905	Flumatinib mesylate	Inhibitor	99.87%	Phase 4
HY-50905	Dovitinib	Inhibitor	99.94%	Phase 3
HY-16961	Sitravatinib	Inhibitor	99.59%	Phase 3
HY-10205	Cediranib		99.58%	Phase 3
HY-145557	Bezuclastinib	Inhibitor	98.59%	Phase 3
HY-136256	Vimseltinib	Inhibitor	99.08%	Phase 3
HY-13049	Cediranib maleate		99.95%	Phase 3
HY-10228	Motesanib	Inhibitor	99.96%	Phase 3
HY-108713	Famitinib		98.43%	Phase 3
HY-124526	Chiauranib	Inhibitor	99.28%	Phase 3
HY-10207	Dovitinib lactate	Inhibitor	99.62%	Phase 3
HY-10229	Motesanib Diphosphate	Inhibitor	99.64%	Phase 3
HY-152839	Elenestinib	Inhibitor	98.82%	Phase 3
HY-16961A	Sitravatinib malate	Inhibitor	/	Phase 3
HY-B0062	Dovitinib lactate hydrate	Inhibitor	/	Phase 3
HY-108713A	Famitinib malate		/	Phase 3
HY-13024	Rebastinib		99.91%	Phase 2
HY-109086	Edicotinib	Inhibitor	98.78%	Phase 2
HY-10206	Amuvatinib		99.47%	Phase 2
HY-109190	Seralutinib	Inhibitor	99.77%	Phase 2
HY-10202	Tandutinib		99.48%	Phase 2
HY-10527	Telatinib	Inhibitor	99.60%	Phase 2
HY-10202A	Tandutinib hydrochloride		99.78%	Phase 2
HY-10527C	Telatinib mesylate	Inhibitor	99.46%	Phase 2
HY-10206A	Amuvatinib hydrochloride	Inhibitor	/	Phase 2
HY-10204	OSI-930		98.57%	Phase 1
HY-12010	BMS-599626 Hydrochloride	Inhibitor	99.68%	Phase 1
HY-10251	BMS-599626	Inhibitor	/	Phase 1

抗体抑制剂 (1)

目录号	产品名	作用方式	纯度	Phase
HY-P99462	Barzolvolimab	Inhibitor	99.78%	Phase 2

Pre-clinical Phase

生物活性分子 (88)

Cat. No.	产品名	作用方式	纯度	是否罕见病
HY-10514	BX795		99.17%	否
HY-101443	ISCK03	Inhibitor	99.50%	否
HY-131339	SP-96	Inhibitor	99.42%	否
HY-10501	SU14813	Inhibitor	99.63%	否
HY-132166	M4205	Inhibitor	99.47%	否
HY-112802	AZD3229	Inhibitor	99.69%	否
HY-13894	Tyrphostin AG1296		99.69%	否
HY-G0017	N-Desmethyl imatinib		99.16%	否
HY-13838	PLX647	Inhibitor	99.79%	否
HY-10408	Ki20227	Inhibitor	99.17%	否
HY-10873	N-Desethyl Sunitinib		99.63%	否
HY-15240	c-Kit-IN-1	Inhibitor	98.83%	否
HY-I0678	Regorafénib N-oxyde (M2)		98.27%	否
HY-10501A	SU14813 maleate	Inhibitor	99.04%	否
HY-101219	VEGFR-IN-1	Inhibitor	98.42%	否
HY-112452	SU11652		99.06%	否
HY-15463S1	Imatinib-d4		99.97%	否
HY-15813	FIIN-1	Inhibitor	99.11%	否
HY-148794	Risvodetinib	Inhibitor	99.21%	否
HY-103274	PD180970		99.27%	否
HY-13493	AC710	Inhibitor	98.56%	否
HY-112615	NAMPT inhibitor-linker 1		98.08%	否
HY-13016S	Cabozantinib-d6		98.14%	否
HY-103032	Multi-kinase inhibitor 1	Inhibitor	99.34%	否
HY-112616	NAMPT inhibitor-linker 2	Inhibitor	98.11%	否
HY-10981S	Lenvatinib-d4	Inhibitor	99.59%	否
HY-133980A	O-Demethyl Lenvatinib hydrochloride		95.54%	否
HY-138813	N-Desethyl Sunitinib hydrochloride		99.77%	否
HY-15463S	Imatinib-d8		99.85%	否
HY-18302	c-Kit-IN-5-1	Inhibitor	98.16%	否
HY-18179	AZD2932	Inhibitor	99.04%	否
HY-112802A	AZD3229 Tosylate	Inhibitor	99.80%	否
HY-10208S	Pazopanib-d6		≥98.0%	否
HY-10230S	Midostaurin-d5	Inhibitor	≥98.0%	否
HY-12009S	Pazopanib-13C,d3 hydrochloride		97.51%	否
HY-123450	S116836		99.65%	否
HY-133980	O-Demethyl Lenvatinib		/	否
HY-136201	Sodium Glucoheptonate		≥98.0%	否
HY-15198	KG5	Inhibitor	99.79%	否
HY-15463S2	Imatinib-d3 hydrochloride		95.19%	否
HY-156619	Labuxtinib	Inhibitor	99.76%	否
HY-160765	WNTinib		/	否
HY-18317	JNJ-38158471	Inhibitor	97.02%	否
HY-101034	CHMFL-ABL/KIT-155		/	否
HY-128589	CHMFL-KIT-033	Inhibitor	/	否
HY-128602	c-Kit-IN-2	Inhibitor	/	否
HY-10873S	N-Desethyl Sunitinib-d5		/	否
HY-10201S2	Sorafenib-13C,d3		98.35%	否
HY-10208S1	Pazopanib-13C,d3		/	否
HY-10331S	Regorafenib-d3		≥98.0%	否
HY-10331S1	Regorafenib-13C,d3		/	否
HY-10981S1	Lenvatinib-d5	Inhibitor	/	否
HY-110071	APcK110	Inhibitor	/	否
HY-110272	Vatalanib succinate	Inhibitor	/	否
HY-110293	CHMFL-FLT3-122		/	否
HY-117873	KBP-7018	Inhibitor	/	否
HY-13016S1	Cabozantinib-d4		/	否
HY-131275	Imatinib Impurity E		96.05%	否
HY-132451S	(R,S)-4-Hydroxy Cyclophosphamide-d4 Preparation Kit		/	否
HY-13342AS	Apatinib-d8 free base		92.56%	否
HY-13645	Henatinib	Inhibitor	/	否
HY-13838A	PLX647 dihydrochloride	Inhibitor	/	否
HY-13904S	Flumatinib-d3	Inhibitor	/	否
HY-139996	Pomalidomide-C5-Dovitinib		/	否
HY-143894	FLT3-IN-11	Inhibitor	/	否
HY-143895	FLT3-IN-12	Inhibitor	/	否
HY-147864	c-Fms-IN-12		/	否
HY-149019	Antitumor agent-70		/	否
HY-149415	Multi-kinase-IN-5	Inhibitor	/	否
HY-150026	Multi-kinase-IN-2		/	否
HY-156470	Multi-kinase-IN-6		/	否
HY-15814	HG-7-85-01		99.94%	否
HY-160689	GW694590A	Inhibitor	/	否
HY-18949	JI6	Inhibitor	/	否
HY-50905S	Dovitinib-d8	Inhibitor	/	否
HY-G0017A	N-Desmethyl imatinib mesylate		/	否
HY-G0017S1	N-Desmethyl imatinib-d4		/	否
HY-I0678S	Regorafénib N-oxyde-d3 (M2)		/	否
HY-I0678S1	Regorafénib N-oxyde (M2)-13C,d3		/	否
HY-RS07319	KIT Human Pre-designed siRNA Set A	Pre-designed Sets	/	否
HY-RS07320	Kit Mouse Pre-designed siRNA Set A	Pre-designed Sets	/	否
HY-RS07321	Kit Rat Pre-designed siRNA Set A	Pre-designed Sets	/	否
HY-10330S	Toceranib-d8	Inhibitor	/	否
HY-10981S2	Lenvatinib-15N,d4	Inhibitor	/	否
HY-116116	Tafetinib	Inhibitor	/	否
HY-13493A	AC710 Mesylate	Inhibitor	/	否
HY-W143698	PDGFRα kinase inhibitor 2	Inhibitor	/	否
HY-111947	c-Fms-IN-6	Inhibitor	/	否

直系同源

种属	基因名	来源	基因 ID
Homo sapiens	KIT	NCBI	NCBI:3815
Canis familiaris	KIT	NCBI	NCBI:403811
Mus musculus	KIT	NCBI	NCBI:16590
Rattus norvegicus	KIT	NCBI	NCBI:64030

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