2. GPCR/G Protein Neuronal Signaling
  3. Dopamine Receptor Adrenergic Receptor 5-HT Receptor
  4. LY125180

LY125180 是一种血清素摄取 (serotonin uptake) 抑制剂。LY125180 竞争性抑制皮质突触体对血清素和去甲肾上腺素的摄取以及纹状体突触体对多巴胺的摄取，Ki 值分别为 0.06 μM、2.2 μM 和 2.5 μM。

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LY125180 Chemical Structure

LY125180 Chemical Structure

CAS No. : 74515-39-2

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LY125180 相关抗体

Top Publications Citing Use of Products

查看 Dopamine Receptor 亚型特异性产品:

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Dopamine Receptor D1 Receptor D2 Receptor D3 Receptor D4 Receptor D5 Receptor

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

LY125180 is a serotonin uptake inhibitor. LY125180 competitively inhibits the uptake of serotonin and norepinephrine by cortical synaptosomes and of dopamine by striatal synaptosomes, with Ki values of 0.06 μM, 2.2 μM and 2.5 μM respectively[1].

分子量

305.84

Formula

C18H24ClNO
CAS 号
Unlabeled CAS

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

LY125180 相关分类

  • 摩尔计算器

  • 稀释计算器

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

LY12518074515-39-2LY 125180LY-125180Dopamine ReceptorAdrenergic Receptor5-HT ReceptorBeta ReceptorSerotonin Receptor5-hydroxytryptamine Receptorserotonin uptake inhibitorInhibitorinhibitorinhibit

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目录号：
HY-129682
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