MZ82， Ko 143 (HY-10010) 衍生物，是一种 ATP 结合盒亚家族 G 成员2 (ABCG2/BCRP) 抑制剂，IC50 值约 23 nM。与 Ko 143 (HY-10010) 相比，MZ82 不仅在肝微粒体中表现出极大的代谢稳定性，而且在小鼠中也表现出极大的改善，并且能够渗透到大脑中。
Nocarnickelamide B (Compound 2) 是一种线性肽类 ROCK1/2 抑制剂。Nocarnickelamide B 对 ROCK1 和 ROCK2 具有双重抑制活性，其 IC50 值分别为 14.9 μM 和 21.9 μM。Nocarnickelamides B 结合于 ATP 结合位点。Nocarnickelamide B 抑制 ROCK 调控的细胞骨架收缩标志物，如肌球蛋白轻链的激活。Nocarnickelamide B 可用于青光眼研究。
Allosteric kinase inhibition is among the most promising and sensitive deactivation mechanism of kinase activity. A unique collection of 4,800 carefully selected molecules via docking and visual evaluation has been offered.
Nocarnickelamide B (Compound 2) 是一种线性肽类 ROCK1/2 抑制剂。Nocarnickelamide B 对 ROCK1 和 ROCK2 具有双重抑制活性，其 IC50 值分别为 14.9 μM 和 21.9 μM。Nocarnickelamides B 结合于 ATP 结合位点。Nocarnickelamide B 抑制 ROCK 调控的细胞骨架收缩标志物，如肌球蛋白轻链的激活。Nocarnickelamide B 可用于青光眼研究。
ATP synthase alpha chain; ATP synthase alpha chain; mitochondrial; ATP synthase subunit alpha; ATP synthase subunit alpha mitochondrial; ATP synthase; H+ transporting; mitochondrial F1 complex; alpha subunit 1; cardiac muscle; ATP synthase; H+ transporting; mitochondrial F1 complex; alpha subunit; 1; ATP synthase; H+ transporting; mitochondrial F1 complex; alpha subunit; isoform 1; cardiac muscle; ATP synthase; H+ transporting; mitochondrial F1 complex; alpha subunit; isoform 2; non-cardiac muscle-like 2; ATP sythase F1 ATPase; alpha subunit; ATP5A; ATP5a1; ATP5AL2; ATPA_HUMAN; ATPM; Epididymis secretory sperm binding protein Li 123m; hATP1; HEL-S-123m; MC5DN4; mitochondrial; Mitochondrial ATP synthetase; Mitochondrial ATP synthetase oligomycin resistant; Modifier of Min 2; Modifier of Min 2 mouse homolog; Modifier of Min 2; mouse; homolog of; MOM2; OMR; ORM; OTTHUMP00000163475
CLPX Antibody (YA2814) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2814), targeting CLPX, with a predicted molecular weight of 69 kDa (observed band size: 69 kDa). CLPX Antibody (YA2814) can be used for WB, ICC/IF experiment in human, mouse, rat, hamster background.
ABCB5 P-gp; ATPbinding cassette sub family B (MDR/TAP) member 5; P glycoprotein ABCB5
WB, ICC/IF
Human
ABCB5 Antibody (YA836) is a non-conjugated and Mouse origined monoclonal antibody about 139 kDa, targeting to ABCB5 (8D2). It can be used for WB,ICC/IF assays with tag free, in the background of Human.
ATP-binding cassette transporter 8; White protein homolog; ABC8; WHT1; ABCG1; ABC transporter 8; WHITE1
WB
Human
ABCG1 Antibody (YA1841) is a non-conjugated IgG antibody, targeting ABCG1, with a predicted molecular weight of 76 kDa (observed band size: 100 kDa). ABCG1 Antibody (YA1841) can be used for WB experiment in human background.
G3BP1; G3BP; Ras GTPase-activating protein-binding protein 1; G3BP-1; ATP-dependent DNA helicase VIII; hDH VIII; GAP SH3 domain-binding protein 1
WB, IHC-P, ICC/IF, IP, FC
Human, Mouse, Rat
G3BP Antibody (YA2432) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2432), targeting G3BP, with a predicted molecular weight of 52 kDa (observed band size: 68 kDa). G3BP Antibody (YA2432) can be used for WB, IHC-P, ICC/IF, IP, FC experiment in human, mouse, rat background.
ATP synthase lipid-binding protein; ATP synthase membrane subunit c locus 1
WB, ICC/IF
Human
ATP Synthase C Antibody (YA1633) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA1633), targeting ATP Synthase C, with a predicted molecular weight of 14 kDa (observed band size: 14 kDa). ATP Synthase C Antibody (YA1633) can be used for WB, ICC/IF experiment in human background.
ATP synthase lipid-binding protein; ATP synthase membrane subunit c locus 1
WB, IHC-P, IP
Human, Rat
ATP5G Antibody (YA2205) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2205), targeting ATP5G, with a predicted molecular weight of 14 kDa (observed band size: 14 kDa). ATP5G Antibody (YA2205) can be used for WB, IHC-P, IP experiment in human, rat background.
ABCF1 Antibody (YA2712) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA2712), targeting ABCF1, with a predicted molecular weight of 96 kDa (observed band size: 96 kDa). ABCF1 Antibody (YA2712) can be used for WB, IHC-P, ICC/IF experiment in human, rat background.
ABC30 antibody;
abcC2 antibody;
ATPbinding cassette sub family C (CFTR/MRP) member 2 antibody;
ATPbinding cassette subfamily C member 2 antibody;
ATP-binding cassette sub-family C member 2 antibody;
Canalicular multidrug resistance protein antibody;
Canalicular multispecific organic anion transporter 1 antibody;
CMOAT antibody;
CMOAT1 antibody;
cMRP antibody;
DJS antibody;
KIAA1010 antibody;
MRP 2 antibody;
MRP2_HUMAN antibody;
Multidrug resistance associated protein 2 antibody;
Multidrug resistance-associated protein 2 antibody;
WB, ICC/IF, FC
Human
MRP2/ABCC2 Antibody is an unconjugated, approximately 174 kDa, rabbit-derived, anti-MRP2/ABCC2 monoclonal antibody. MRP2/ABCC2 Antibody can be used for: WB, ICC/IF, FC expriments in human background without labeling.
ABC20; ABCB1; ATPbinding cassette, sub family B(MDR/TAP), member 1; ATP-binding cassette sub-family B member 1; CD243; CLCS; Colchicin sensitivity; Doxorubicin resistance; GP170; MDR1; MDR1_HUMAN; Multidrug resistance 1; Multidrug resistance protein 1; P glycoprotein 1; P gp; PGY1.
CHD4 Antibody (YA946) is a mouse-derived non-conjugated IgG2b antibody (Clone NO.: YA946), targeting CHD4, with a predicted molecular weight of 218 kDa (observed band size: 260 kDa). CHD4 Antibody (YA946) can be used for WB, IP experiment in human background.
CHD4 Antibody (YA947) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA947), targeting CHD4, with a predicted molecular weight of 218 kDa (observed band size: 260 kDa). CHD4 Antibody (YA947) can be used for WB, ICC/IF, FC experiment in human background.
CHD3 Antibody (YA944) is a mouse-derived non-conjugated IgG1 antibody (Clone NO.: YA944), targeting CHD3, with a predicted molecular weight of 227 kDa (observed band size: 260 kDa). CHD3 Antibody (YA944) can be used for WB, ICC/IF, IP experiment in human, mouse, rat background.
CHD3 Antibody (YA945) is a rabbit-derived non-conjugated IgG antibody (Clone NO.: YA945), targeting CHD3, with a predicted molecular weight of 227 kDa (observed band size: 260 kDa). CHD3 Antibody (YA945) can be used for WB, IHC-P, ICC/IF, FC experiment in human, mouse, rat background.
XRCC5; G22P2; X-ray repair cross-complementing protein 5; 86 kDa subunit of Ku antigen; ATP-dependent DNA helicase 2 subunit 2; ATP-dependent DNA helicase II 80 kDa subunit; CTC box-binding factor 85 kDa subunit; CTC85; CTCBF; DNA repair pr
WB, ICC/IF, IP, ChIP
Human, Monkey
Ku80 Antibody (YA714) is a non-conjugated and Mouse origined monoclonal antibody about 83 kDa, targeting to Ku80 (8H1). It can be used for WB,ICC/IF,IP,ChIP assays with tag free, in the background of Human, Monkey.
p-pg; PGP; ABCB1; MDR1; PGY1; Multidrug resistance protein 1; ATP-binding cassette sub-family B member 1; P-glycoprotein 1; CD antigen CD243
WB
Human
P Glycoprotein Antibody is a non-conjugated and Rabbit origined monoclonal antibody about 141 kDa, targeting to P Glycoprotein. It can be used for WB assays with tag free, in the background of Human.
ATP dependent DNA helicase II 80 kDa subunit; ATP dependent DNA helicase II 86 Kd subunit; ATP dependent DNA helicase II; ATP-dependent DNA helicase 2 subunit 2; ATP-dependent DNA helicase II 80 kDa subunit; CTC box binding factor 85 kDa; CTC box-binding factor 85 kDa subunit; CTC85; CTCBF; DNA repair protein XRCC5; Double strand break rejoining; FLJ39089; G22P2; KARP 1; KARP1; Ku 80; Ku autoantigen 80kDa; Ku80; Ku86; Ku86 autoantigen related protein 1; KUB 2; KUB2; Lupus Ku autoantigen protein p86; NFIV; Nuclear factor IV; Thyroid lupus autoantigen; Thyroid-lupus autoantigen; TLAA; X ray repair complementing defective repair in Chinese hamster cells 5; double strand break rejoining; X-ray repair complementing defective repair in Chinese hamster cells 5; double-strand-break rejoining; X-ray repair cross-complementing protein 5; Xray repair complementing defective repair in Chinese hamster cells 5; XRCC 5; XRCC5; XRCC5_HUMAN.
