1. Signaling Pathways
  2. Membrane Transporter/Ion Channel
  3. ATP Synthase

ATP Synthase

ATPases are a class of enzymes that catalyze the decompositionof ATP into ADP and a free phosphate ion. This dephosphorylation reaction releases energy, which the enzyme (in most cases) harnesses to drive other chemical reactions that would not otherwise occur. Some such enzymes are integral membrane proteins and move solutes across the membrane, typically against their concentration gradient. These are called transmembrane ATPases. Transmembrane ATPases import many of the metabolites necessary for cell metabolism and export toxins, wastes, and solutes that can hinder cellular processes. Such as the sodium-potassium exchanger (or Na+/K+ ATPase) and the hydrogen potassium ATPase (H+/K+ ATPase or gastric proton pump) that acidifies the contents of the stomach.

ATP Synthase 相关产品 (6):

Cat. No. Product Name Effect Purity
  • HY-16589
    Oligomycin A Inhibitor 99.94%
    Oligomycin A 是从链霉菌属中得到的一种线粒体 F0F1-ATPase 抑制剂,Ki 值为 1 μM;Oligomycin A 具有抗真菌的功能。
  • HY-111651
    Gboxin Inhibitor 99.32%
    Gboxin 是一种氧化磷酸化抑制剂,可靶向抑制胶质母细胞瘤生长。Gboxin 抑制 F0F1 ATP 合成 。具有抗肿瘤活性。
  • HY-15877
    BTB06584 Inhibitor
  • HY-112715
    ATP synthase inhibitor 1 Inhibitor 99.84%
    ATP synthase inhibitor 1 是一种 F1/FO-ATP 合酶复合物 c 亚基的有效抑制剂,抑制线粒体通透性转换孔的开放,但不影响 ATP 的水平。
  • HY-N6784
    Oligomycin B Inhibitor
    Oligomycin B 是一种从链霉菌属中得到的抗生素,为真核生物 ATP 合成酶 (ATP synthase) 抑制剂,可诱导凋亡。
  • HY-N6782
    Oligomycin Inhibitor
    Oligomycins are macrolides created by Streptomyces species that can be toxic to other organisms through their ability to inhibit mitochondrial membrane-bound ATP synthases. The mitochondrial F1FO ATP synthase can switch to an ATP hydrolase during ischemia, so that, under these conditions, inhibition by oligomycins will reduce ATP depletion rather than block ATP synthesis.
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