1. Signaling Pathways
  2. Anti-infection
  3. Filovirus

Filovirus

Filoviruses is amongst the most lethal of primate pathogens. Filoviruses cause lethal hemorrhagic fever in humans and nonhuman primates. The family Filoviridae includes two genera: Marburgvirus, comprising various strains of the Lake Victoria marburgvirus (MARV); and Ebolavirus (EBOVs), comprising four species including Sudan ebolavirus (SEBOV), Zaire ebolavirus (ZEBOV), Ivory Coast ebolavirus (CIEBOV), and Reston ebolavirus (REBOV); and a tentative species Bundibugyo ebolavirus (BEBOV).

The infections typically affect multiple organs in the body and are often accompanied by hemorrhage (bleeding). Once the virus has been transmitted from an animal host to a human, it can then spread through person-to-person contact.

Filovirus 相关产品 (5):

Cat. No. Product Name Effect Purity
  • HY-10221
    Vorinostat Inhibitor 99.90%
    Vorinostat (SAHA) 是一种有效的,可口服的 HDAC1HDAC2HDAC3 (Class I)HDAC7 (Class II)Class IV (HDAC11) 的抑制剂,对 HDAC1/3 的 ID50 值分别为 10 nM 和 20 nM。Vorinostat 可以诱导细胞凋亡 (apoptosis)。Vorinostat 还是一种人类乳头瘤病毒 (HPV)-18 DNA 扩增的有效抑制剂。
  • HY-18649A
    Galidesivir Inhibitor 99.29%
    Galidesivir (BCX4430) 是病毒 RdRp 聚合酶抑制剂。Galidesivir 通过与 RdRp 紧密结合来抑制 SARS-CoV-2。
  • HY-18649
    Galidesivir hydrochloride Inhibitor 99.88%
    Galidesivir hydrochloride (BCX 4430 hydrochloride) 是病毒 RdRp 聚合酶抑制剂。Galidesivir hydrochloride 通过与 RdRp 紧密结合来抑制 SARS-CoV-2。
  • HY-113794
    DSHS00884 Inhibitor 98.24%
    DSHS00884 是有效的人乳头瘤病毒 E6 抑制剂,IC50 为 10 μM。
  • HY-13516
    Aloperine Inhibitor >98.0%
    Aloperine 是一种在苦参类 (例如苦豆子 Sophora alopecuroides L) 植物中生物碱,其具有抗癌,抗炎和抗病毒特性。 Aloperine 被广泛用于治疗过敏性接触性皮炎湿疹和其他皮肤炎症。 Aloperine 诱导 HL-60 细胞中诱导凋亡 apoptosis 和自噬 autophagy
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